CYLD and MAP3K7

  • Data Source:
  • BioGRID (pull down, pull down, affinity chromatography technology)

CYLD

MAP3K7

Description CYLD lysine 63 deubiquitinase mitogen-activated protein kinase kinase kinase 7
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Amyotrophic lateral sclerosis (sporadic) ( 24529757)
  • Asthma ( 31959851 29273806)
  • Asthma (adult onset) ( 31036433)
  • Asthma (childhood onset) ( 31036433)
  • Bone mineral density (hip) ( 30172743)
  • Celiac disease ( 20190752)
  • Graves' disease ( 21841780)
  • Response to anti-TNF therapy in rheumatoid arthritis ( 26776603)
  • Response to inhaled corticosteroid treatment in asthma (change in FEV1) ( 24792382)
  • Severity of nausea and vomiting of pregnancy ( 29563502)
Interacting Genes 23 interacting genes: AKT1 AURKB DDX58 DLG4 HDAC6 IKBKE IKBKG ITCH MAP3K7 MAPRE1 PLK4 PTPA TBK1 TP53 TRAF2 TRAF6 TRAF7 TRAIP TRIM47 TUBA1A UBC UBE2D2 UBE2S 67 interacting genes: AKTIP BBS10 BCL10 CARD11 CHUK COPS5 CYLD EIF2AK2 ELP1 EZH2 FOS GPR25 HGS HIPK2 IKBKB IKBKG IL17RD IRAK1 MAP2K4 MAP2K6 MAP3K14 MAP3K3 MAP3K5 MAP4K1 MAP4K4 MAPK14 MAPK6 MAPK8 MAPK8IP1 MAVS MUL1 NAIP NDUFS6 NFKBIA NOD2 NRIP1 PEBP1 PELI3 PINK1 PPM1B PPM1L PPP2R1A PPP5C PRKAB1 RBX1 RELA RNF19A ROR2 SMAD3 SMAD6 SMAD7 STAT3 STRADB TAB1 TAB2 TAB3 TGFBR1 TNFRSF11A TRAF3 TRAF3IP2 TRAF6 UBASH3A UBC VRK2 XIAP ZNF593 ZNF746
Entrez ID 1540 6885
HPRD ID 05427 04011
Ensembl ID ENSG00000083799 ENSG00000135341
Uniprot IDs A0A024R6T1 Q9NQC7 O43318
PDB IDs 1IXD 1WHL 1WHM 2VHF 2EVA 2YIY 4GS6 4L3P 4L52 4L53 4O91 5E7R 5GJD 5GJF 5GJG 5J7S 5J8I 5J9L 5JGA 5JGB 5JGD 5JH6 5JK3 5V5N
Enriched GO Terms of Interacting Partners?
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