CXADR and FAM3C

Data Source:
BioGRID (two hybrid)

		CXADR	FAM3C
Description		CXADR Ig-like cell adhesion molecule	FAM3 metabolism regulating signaling molecule C
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GO Annotations	Cellular Component	Acrosomal Vesicle Extracellular Region Nucleoplasm Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Adherens Junction Bicellular Tight Junction Basolateral Plasma Membrane Apicolateral Plasma Membrane Cell Junction Filopodium Growth Cone Protein-containing Complex Neuron Projection Cell Body Membrane Raft	Extracellular Region Extracellular Space Golgi Apparatus Platelet Dense Granule Lumen Extracellular Exosome
	Molecular Function	Virus Receptor Activity Integrin Binding Protein Binding Beta-catenin Binding PDZ Domain Binding Cell Adhesion Molecule Binding Connexin Binding Cell Adhesive Protein Binding Involved In AV Node Cell-bundle Of His Cell Communication	Cytokine Activity Protein Binding
	Biological Process	Mitochondrion Organization Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Heart Development Germ Cell Migration Epithelial Structure Maintenance Neutrophil Chemotaxis Actin Cytoskeleton Reorganization Cell-cell Junction Organization Gamma-delta T Cell Activation Viral Entry Into Host Cell Cardiac Muscle Fiber Development Regulation Of Immune Response Leukocyte Migration Transepithelial Transport AV Node Cell To Bundle Of His Cell Communication AV Node Cell-bundle Of His Cell Adhesion Involved In Cell Communication Regulation Of AV Node Cell Action Potential	Platelet Degranulation Signal Transduction Multicellular Organism Development Biological_process Negative Regulation Of Gluconeogenesis
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Cell surface interactions at the vascular wall	Platelet degranulation
Drugs
Diseases
GWAS		Neutrophil count ( 32888494)	Biomedical quantitative traits ( 19396169) Bone mineral density (paediatric, lower limb) ( 24945404) Bone mineral density (paediatric, skull) ( 24945404) Bone mineral density (paediatric, total body less head) ( 24945404) Bone mineral density (paediatric, upper limb) ( 24945404) Calcaneus stiffness index ( 30779856) Forearm bone mineral density ( 26367794) Hand grip strength ( 27325353) Heel bone mineral density ( 30598549 28869591) Lung adenocarcinoma ( 28604730) Pediatric bone mineral content (radius) ( 26041818) Phenylephrine infusion rate during anesthesia ( 31455332) Total body bone mineral density ( 30172743) Ulna and radius bone mineral density ( 30172743)
Interacting Genes		10 interacting genes: ANKRD46 EWSR1 FAM3C JAML LNX1 LNX2 MAL NCOA1 NCOR1 VKORC1	48 interacting genes: AHNAK2 BIK BNIP2 CLEC17A CLEC2D CLEC4E CREB3 CREB3L1 CXADR CYB5R3 ELOVL4 ERGIC3 EVI2B FAM209A FCGR1A FCGRT FFAR2 FKBP7 GGT6 GJB5 GPR42 GPX8 HHLA2 KCNA2 KIR2DL3 LMNA LRRC25 MFF PDZK1IP1 RELL2 RMDN3 RNASEH1 SAR1A SCN3B SLC10A6 SLC16A2 SLC18A1 SLC35C2 SPINT1 SSMEM1 STX1A TEX29 TMEM248 TMEM45B TMEM71 TMEM80 TMPRSS2 TMX2
Entrez ID		1525	10447
HPRD ID		11804	12270
Ensembl ID		ENSG00000154639	ENSG00000196937
Uniprot IDs		P78310	Q92520
PDB IDs		1EAJ 1F5W 1JEW 1KAC 1P69 1P6A 1RSF 2J12 2J1K 2NPL 2W9L 2WBW 3J6L 3J6M 3J6N 3J6O	5LC2
Enriched GO Terms of Interacting Partners?
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