UBE2U and RNF113A

Data Source:
BioGRID (two hybrid)

		UBE2U	RNF113A
Description		ubiquitin conjugating enzyme E2 U	ring finger protein 113A
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GO Annotations	Cellular Component	HULC Complex	Nucleus Nucleoplasm U2-type Spliceosomal Complex Nuclear Speck U2-type Precatalytic Spliceosome
	Molecular Function	Protein Binding ATP Binding Ubiquitin Conjugating Enzyme Activity	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Polyubiquitination DNA Repair Histone Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	MRNA Splicing, Via Spliceosome DNA Repair Protein Ubiquitination Isopeptide Cross-linking Via N6-glycyl-L-lysine SnoRNA Splicing Negative Regulation Of Chemokine-mediated Signaling Pathway
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Severe bacterial meningitis ( 31092817)
Interacting Genes		68 interacting genes: ANAPC11 BARD1 BFAR CADPS2 CBL CGRRF1 DTX1 DZIP3 GOLGA2 KAT6A MDM2 MIB1 MIB2 MID2 MKRN3 MUL1 PCGF1 PCGF2 PCGF6 PJA1 PML RBCK1 RNF10 RNF11 RNF113A RNF113B RNF114 RNF125 RNF139 RNF14 RNF144B RNF150 RNF166 RNF17 RNF170 RNF181 RNF2 RNF25 RNF26 RNF41 RNF5 RNFT1 SYVN1 TRAIP TRIM15 TRIM2 TRIM23 TRIM24 TRIM27 TRIM28 TRIM3 TRIM32 TRIM34 TRIM35 TRIM37 TRIM38 TRIM46 TRIM47 TRIM5 TRIM54 TRIM63 TRIM65 TRIM68 TRIM74 UBA1 VPS11 VPS41 ZSWIM2	8 interacting genes: CCAR1 CXCR4 ILF3 RBM39 SNRNP200 TERF2 TRIM8 UBE2U
Entrez ID		148581	7737
HPRD ID		14599	06760
Ensembl ID		ENSG00000177414	ENSG00000125352
Uniprot IDs		A0A140VJY9 Q5VVX9	O15541
PDB IDs		1YRV	5Z56 5Z58 6FF4 6FF7
Enriched GO Terms of Interacting Partners?
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