CREB3L4 and GANAB

Data Source:
BioGRID (two hybrid)

		CREB3L4	GANAB
Description		cAMP responsive element binding protein 3 like 4	glucosidase II alpha subunit
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Chromatin Nucleus Nucleoplasm Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Integral Component Of Membrane Nuclear Membrane	Endoplasmic Reticulum Lumen Golgi Apparatus Membrane Glucosidase II Complex Melanosome Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding CAMP Response Element Binding Sequence-specific Double-stranded DNA Binding	RNA Binding Hydrolase Activity, Hydrolyzing O-glycosyl Compounds Protein Binding Carbohydrate Binding Glucan 1,3-alpha-glucosidase Activity Alpha-glucosidase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Spermatogenesis Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Transcription By RNA Polymerase II	Carbohydrate Metabolic Process Protein Folding N-glycan Processing
Pathways		CREB3 factors activate genes	N-glycan trimming in the ER and Calnexin/Calreticulin cycle Calnexin/calreticulin cycle Maturation of spike protein Maturation of spike protein
Drugs			Miglitol
Diseases
GWAS		Age at first birth ( 27798627) Blood protein levels ( 30072576 29875488) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cooked vegetable consumption ( 32066663) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Empathy quotient ( 29527006) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		5 interacting genes: GANAB GET3 LRRC4C SLC19A3 SOX9	9 interacting genes: CCNH CREB3L4 CSNK2A1 LINC01554 MAPK8 PRKCSH PRRC2A PTPRC RAP1A
Entrez ID		148327	23193
HPRD ID		06323	03516
Ensembl ID		ENSG00000143578	ENSG00000089597
Uniprot IDs		Q8TEY5	B4DIW2 B4DSM6 B4DZ53 E9PKU7 F5H6X6 Q14697 V9HWJ0
PDB IDs
Enriched GO Terms of Interacting Partners?
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