CSPG4 and GRIP2

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid, in vivo)

		CSPG4	GRIP2
Description		chondroitin sulfate proteoglycan 4	glutamate receptor interacting protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Ruffle Extracellular Region Nucleoplasm Golgi Lumen Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Cell Surface Apical Plasma Membrane Lamellipodium Membrane Lysosomal Lumen Collagen-containing Extracellular Matrix Extracellular Exosome	Cytosol Plasma Membrane
	Molecular Function	Coreceptor Activity Protein Kinase Binding	Signaling Receptor Complex Adaptor Activity
	Biological Process	Activation Of MAPK Activity Angiogenesis Substrate-dependent Cell Migration Cell Population Proliferation Glial Cell Migration Chondroitin Sulfate Biosynthetic Process Chondroitin Sulfate Catabolic Process Dermatan Sulfate Biosynthetic Process Intracellular Signal Transduction Platelet-derived Growth Factor Receptor Signaling Pathway Tissue Remodeling Positive Regulation Of Peptidyl-tyrosine Phosphorylation Ruffle Assembly	Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane
Pathways		A tetrasaccharide linker sequence is required for GAG synthesis Chondroitin sulfate biosynthesis Dermatan sulfate biosynthesis CS/DS degradation Defective B4GALT7 causes EDS, progeroid type Defective B3GAT3 causes JDSSDHD Defective CHST3 causes SEDCJD Defective CHST14 causes EDS, musculocontractural type Defective CHSY1 causes TPBS Defective B3GALT6 causes EDSP2 and SEMDJL1	Trafficking of GluR2-containing AMPA receptors
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31015462) Intraocular pressure ( 29617998) Simvastatin-induced myopathy ( 31220337)	Cognitive performance ( 19734545) SjÃ¶gren's syndrome ( 28076899)
Interacting Genes		9 interacting genes: ATF7IP BCAR1 C1QA CDC42 GRIP1 GRIP2 MPDZ PTK2 TNK2	4 interacting genes: CSPG4 GFI1B GRIA2 GRIA3
Entrez ID		1464	80852
HPRD ID		03105	18994
Ensembl ID		ENSG00000173546	ENSG00000144596
Uniprot IDs		Q6UVK1	Q9C0E4
PDB IDs			1V62 1X5R
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?