RNF151 and FGF12

Data Source:
BioGRID (two hybrid)

		RNF151	FGF12
Description		ring finger protein 151	fibroblast growth factor 12
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Extracellular Space Nucleus Cytoplasm Synapse
	Molecular Function	Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Growth Factor Activity Sodium Channel Regulator Activity Ion Channel Binding
	Biological Process	Spermatogenesis Protein Ubiquitination Cell Differentiation	Regulation Of Membrane Depolarization Signal Transduction Cell-cell Signaling Chemical Synaptic Transmission Nervous System Development Heart Development Adult Locomotory Behavior Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Sodium Ion Transport Neuromuscular Process Cardiac Muscle Cell Action Potential Involved In Contraction Regulation Of Neuronal Action Potential Regulation Of Sodium Ion Transmembrane Transport Regulation Of Voltage-gated Sodium Channel Activity Regulation Of Sodium Ion Transmembrane Transporter Activity Negative Regulation Of Cation Channel Activity
Pathways			Phase 0 - rapid depolarisation
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)	Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Bipolar disorder ( 31043756) Gut microbiota relative abundance (Ruminococcus belonging to family Erysipelotrichaceae) ( 33208821) Hip circumference adjusted for BMI ( 28552196) Idiopathic dilated cardiomyopathy ( 29495422) Ileal carcinoids ( 21139019) Major depressive disorder ( 23377640) Metabolite levels ( 19043545) Post bronchodilator FEV1/FVC ratio ( 26634245) PR interval ( 32439900) Serum metabolite concentrations in chronic kidney disease ( 29545352) Severe influenza A (H1N1) infection ( 26379185) Sleep quality ( 23728906)
Interacting Genes		18 interacting genes: ABT1 APP C1orf35 CT45A1 DVL3 FAM133A FAM9A FGF12 NKAPD1 PIBF1 PRPF3 SCARA5 SREK1IP1 TSPYL2 UBC UBE2D2 UBE2I ZC4H2	25 interacting genes: APP COIL CT45A1 DACH1 DCTD DPPA2 GRIP1 IKZF1 LZTS2 MAPK13 MAPK8IP2 NEDD4 NEDD4L PJA1 RBAK RNF151 RP9 SMURF1 SRPK1 SRPK2 STAC3 THAP1 YWHAE ZNF460 ZNF79
Entrez ID		146310	2257
HPRD ID		19116	03303
Ensembl ID		ENSG00000179580	ENSG00000114279
Uniprot IDs		H3BNJ8 Q2KHN1	P61328
PDB IDs			1Q1U 4JQ0
Enriched GO Terms of Interacting Partners?
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