FAM161B and CBY1

Data Source:
BioGRID (two hybrid)

		FAM161B	CBY1
Description		FAM161 centrosomal protein B	chibby family member 1, beta catenin antagonist
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasmic Microtubule Cilium Microtubule Cytoskeleton	Nucleus Nucleoplasm Trans-Golgi Network Centriole Cytosol Nuclear Speck Cell Projection
	Molecular Function	Protein Binding	Protein Binding Beta-catenin Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Biological_process Cilium Organization	Protein Localization Cell Projection Organization Negative Regulation Of Wnt Signaling Pathway Fat Cell Differentiation Negative Regulation Of Transcription, DNA-templated Protein Homotetramerization Cardiac Muscle Cell Differentiation
Pathways			Deactivation of the beta-catenin transactivating complex
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Serum uric acid levels ( 29559957)	Resting heart rate ( 27798624) Sleep duration ( 30846698)
Interacting Genes		70 interacting genes: ABI2 BICD2 BLOC1S2 BORCS6 CARD9 CBY1 CCDC125 CCDC13 CCDC136 CCDC138 CCDC172 CCDC57 CCDC83 CCDC88B CDR2L CEP55 CEP70 CINP CTNNA3 DDI1 EXOSC8 GAS8 GOLGA2 GOLGA6A GOLGA6L9 GPSM1 HAUS1 HOMER3 HOOK2 HSF2BP ISY1-RAB43 KIAA1328 LZTS1 MAPRE3 MDFI MEIS3 MID2 MIPOL1 MTUS2 NDUFB7 NECAB2 NR3C1 OIP5 PICK1 PLAGL2 PNMA1 PPP2R3C RINT1 SH3BP5L SMAD2 SPDEF SRGAP2B STX11 STX1B SYCE1 TEX11 TEX12 TFIP11 TRAF1 TRAF2 TRIM15 TSGA10 TSNAXIP1 TTC23 TTC23L USH1G USHBP1 VPS52 ZC4H2 ZRANB1	18 interacting genes: AGTPBP1 CDK6 CFAP53 CIBAR1 CLU CTNNB1 DDIAS DZIP1L ENKD1 FAM161B GORASP2 LNX1 NBPF11 RALBP1 RASSF10 TNFAIP8L3 TSG101 TTC23L
Entrez ID		145483	25776
HPRD ID		12649	09676
Ensembl ID		ENSG00000156050	ENSG00000100211
Uniprot IDs		Q96MY7	A0A024R1L9 A0A087WUW0 Q9Y3M2
PDB IDs			4WRQ
Enriched GO Terms of Interacting Partners?
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