CSF2 and DPP7

Data Source:
BioGRID (biochemical)

		CSF2	DPP7
Description		colony stimulating factor 2	dipeptidyl peptidase 7
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Intracellular Membrane-bounded Organelle	Extracellular Region Golgi Apparatus Cytosol Vesicle Azurophil Granule Lumen Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Cytokine Activity Granulocyte Macrophage Colony-stimulating Factor Receptor Binding Protein Binding Growth Factor Activity	Aminopeptidase Activity Serine-type Peptidase Activity Dipeptidyl-peptidase Activity
	Biological Process	MAPK Cascade Histamine Secretion Embryonic Placenta Development Immune Response Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Positive Regulation Of Macrophage Derived Foam Cell Differentiation Cytokine-mediated Signaling Pathway Myeloid Cell Differentiation Neutrophil Differentiation Monocyte Differentiation Macrophage Differentiation Positive Regulation Of Interleukin-23 Production Response To Silicon Dioxide Response To Fluid Shear Stress Epithelial Fluid Transport Macrophage Activation Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Myeloid Dendritic Cell Differentiation Regulation Of Circadian Sleep/wake Cycle, Sleep Regulation Of Myeloid Cell Differentiation Negative Regulation Of Transcription, DNA-templated Cellular Response To Lipopolysaccharide Positive Regulation Of Podosome Assembly Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus Dendritic Cell Differentiation Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand	Proteolysis Neutrophil Degranulation
Pathways		Interleukin-3, Interleukin-5 and GM-CSF signaling RAF/MAP kinase cascade Interleukin-10 signaling RUNX1 regulates transcription of genes involved in differentiation of myeloid cells Interleukin receptor SHC signaling	Neutrophil degranulation
Drugs		KB002
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908 23128233) Rheumatoid arthritis ( 30423114 22446963 24390342) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)	Blood protein levels ( 29875488) Pursuit maintenance gain ( 29064472)
Interacting Genes		7 interacting genes: CSF2RA CSF2RB IL3RA KITLG MEOX2 PRG2 SDC2	1 interacting genes: XRN1
Entrez ID		1437	29952
HPRD ID		00734	07634
Ensembl ID		ENSG00000164400	ENSG00000176978
Uniprot IDs		P04141	Q9UHL4
PDB IDs		1CSG 2GMF 4NKQ 4RS1 5C7X 5D70 5D71 5D72 6BFQ 6BFS	3JYH 3N0T 4EBB
Enriched GO Terms of Interacting Partners?
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