UBXN2B and XAF1

Data Source:
BioGRID (two hybrid)

		UBXN2B	XAF1
Description		UBX domain protein 2B	XIAP associated factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Golgi Apparatus Cytosol Spindle Pole Centrosome	Nucleoplasm Mitochondrion Cytosol
	Molecular Function	Protein Binding Ubiquitin Binding	Protein Binding Zinc Ion Binding
	Biological Process	Autophagosome Assembly Establishment Of Mitotic Spindle Orientation Golgi Organization Nuclear Envelope Reassembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Mitotic Centrosome Separation Membrane Fusion Negative Regulation Of Protein Localization To Centrosome	Apoptotic Process Response To Interferon-beta Type I Interferon Signaling Pathway
Pathways			Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Gallstone disease ( 27094239) LDL cholesterol levels ( 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Loneliness ( 27629369) Low density lipoprotein cholesterol levels ( 29403010) Medication use (HMG CoA reductase inhibitors) ( 31015401) Narcolepsy with cataplexy ( 23496005) Systolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415) Total cholesterol levels ( 29403010) Triglyceride levels ( 30698716) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
Interacting Genes		14 interacting genes: CRX FAM104A INCA1 MEOX1 MEOX2 NGLY1 PAX5 PAX6 PIN1 PPP1R11 UBXN6 VAT1L VCP XAF1	18 interacting genes: AKT1 APP BIRC7 CREBBP GLS2 LRSAM1 RFC5 RNF114 RNF166 SEPHS1 TP53 TRIM21 TRIM50 TRIM54 TRIML2 UBXN2B VCP XIAP
Entrez ID		137886	54739
HPRD ID		18973	06978
Ensembl ID		ENSG00000215114	ENSG00000132530
Uniprot IDs		E5RJ36 Q14CS0	Q6GPH4
PDB IDs			2LXW
Enriched GO Terms of Interacting Partners?
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