STXBP5 and SNAP23

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		STXBP5	SNAP23
Description		syntaxin binding protein 5	synaptosome associated protein 23
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Acetylcholine-gated Channel Complex Synaptic Vesicle SNARE Complex Neuromuscular Junction Extrinsic Component Of Neuronal Dense Core Vesicle Membrane Schaffer Collateral - CA1 Synapse Hippocampal Mossy Fiber To CA3 Synapse Extrinsic Component Of Presynaptic Membrane Presynaptic Cytosol	Nucleoplasm Cytoplasm Mitochondrion Plasma Membrane Adherens Junction Focal Adhesion Phagocytic Vesicle Membrane SNARE Complex Specific Granule Membrane Specific Granule Azurophil Granule Neuron Projection Extracellular Exosome Tertiary Granule Membrane Presynapse
	Molecular Function	GTPase Activator Activity Syntaxin-1 Binding Syntaxin Binding Myosin II Binding	SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Exocytosis Regulation Of Synaptic Vesicle Priming Protein Transport Regulation Of Exocytosis Positive Regulation Of GTPase Activity Positive Regulation Of Exocytosis Regulation Of Protein Secretion Synaptic Vesicle Cycle Regulation Of Synaptic Vesicle Exocytosis	Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Histamine Secretion By Mast Cell Exocytosis Post-Golgi Vesicle-mediated Transport Vesicle Targeting Vesicle Fusion Protein Transport Synaptic Vesicle Priming Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Neutrophil Degranulation Membrane Fusion
Pathways			ER-Phagosome pathway Translocation of SLC2A4 (GLUT4) to the plasma membrane trans-Golgi Network Vesicle Budding Neutrophil degranulation
Drugs
Diseases
GWAS		Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Bronchopulmonary dysplasia ( 23897914) Factor VIII levels ( 30586737) Low vWF levels ( 26486471) Lymphocyte percentage of white cells ( 32888494) Mean platelet volume ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Plasma plasminogen activator levels ( 24578379) Systolic blood pressure ( 30224653) Venous thromboembolism ( 31420334) vWF levels ( 20231535 30586737) White blood cell count ( 32888494)	Bipolar disorder ( 31043756)
Interacting Genes		3 interacting genes: SNAP23 STX1A STX4	32 interacting genes: ABI2 ABI3 CFTR FXR2 ITSN1 KIF5B MATR3 NAPA NAPB PRKCA SCAMP1 SCAMP2 SCGN SNAPIN SNTG1 STX11 STX12 STX1A STX1B STX3 STX4 STX5 STX6 STXBP2 STXBP5 TLK1 VAMP1 VAMP2 VAMP3 VAMP7 VAMP8 WASH2P
Entrez ID		134957	8773
HPRD ID		06845	03962
Ensembl ID		ENSG00000164506	ENSG00000092531
Uniprot IDs		Q5T5C0	A0A024R9R8 A8K287 O00161
PDB IDs			1NHL 3ZUS
Enriched GO Terms of Interacting Partners?
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