TRAM1L1 and BDKRB1

Data Source:
BioGRID (two hybrid)

		TRAM1L1	BDKRB1
Description		translocation associated membrane protein 1 like 1	bradykinin receptor B1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Endoplasmic Reticulum Membrane	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Neuron Projection
	Molecular Function	Protein Binding	G Protein-coupled Receptor Activity Bradykinin Receptor Activity Protein Binding Peptide Binding
	Biological Process	SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation Protein Insertion Into ER Membrane	Negative Regulation Of Protein Phosphorylation Positive Regulation Of Leukocyte Migration Inflammatory Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Response To Mechanical Stimulus Cell Migration Sensory Perception Of Pain Negative Regulation Of Cell Growth Response To Lipopolysaccharide Negative Regulation Of Blood Pressure Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Pathways			Peptide ligand-binding receptors G alpha (q) signalling events G alpha (i) signalling events
Drugs			Ramipril Captopril Zinc Enalaprilat Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Bronchopulmonary dysplasia ( 23897914) Lateral ventricle volume in trauma-exposed individuals ( 29187748) Metabolite levels ( 23823483) Obesity (extreme) ( 19553259) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Visceral adipose tissue adjusted for BMI ( 22589738)	Metabolite levels ( 23823483)
Interacting Genes		29 interacting genes: ASGR2 BDKRB1 BSCL2 CD53 CD79A CD99L2 CLEC1A CLSTN3 CREB3 CREB3L1 CYBC1 ERGIC3 EVI2B FAM209A FKBP7 GPX8 HTR2B LMNA LRRC59 MFF MUC1 PLEKHF2 PLEKHO1 PLPP2 SAR1A TMED8 TMEM52B TMEM79 TMX2	32 interacting genes: C1orf43 CERS1 DNAJB1 GABBR1 GNAQ GRIN1 HHATL HILPDA HTT INSIG1 LAPTM4B LRRC4C MBOAT7 MDC1 NAGPA NAP1L4 NDFIP1 NF2 OAZ2 RAE1 RETREG1 RTN4 SLC25A28 SLC39A14 SLC44A2 SLC6A8 TMEM42 TMX2 TRAM1L1 TRAT1 UQCRC1 ZNF22
Entrez ID		133022	623
HPRD ID		11643	02639
Ensembl ID		ENSG00000174599	ENSG00000100739
Uniprot IDs		Q8N609	P46663
PDB IDs
Enriched GO Terms of Interacting Partners?
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