UROC1 and ALX1

Data Source:
BioGRID (two hybrid)

		UROC1	ALX1
Description		urocanate hydratase 1	ALX homeobox 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol	Chromatin Nucleus Nucleoplasm Golgi Apparatus Nuclear Body
	Molecular Function	Protein Binding Urocanate Hydratase Activity	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Protein Homodimerization Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Histidine Catabolic Process Histidine Catabolic Process To Glutamate And Formamide Histidine Catabolic Process To Glutamate And Formate	Negative Regulation Of Transcription By RNA Polymerase II Neural Crest Cell Migration Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis
Pathways		Histidine catabolism
Drugs
Diseases			Frontonasal dysplasia
GWAS		Anorectal malformation ( 31136621) Cerebellum cortex volume ( 31530798) Fast beta electroencephalogram ( 28040410) Heel bone mineral density ( 30598549) Periventricular white matter hyperintensities ( 32517579) Post bronchodilator FEV1 ( 26634245) Rapid automised naming of letters ( 30741946) Recurrence of malaria infection (mild or asymptomatic) ( 31667592) Waist-to-hip ratio adjusted for BMI ( 28552196)	Bone mineral density (Ward's triangle area) ( 27397699) Brain morphology (MOSTest) ( 32665545) Lung function (FEV1) ( 30061609) Lung function (FVC) ( 30061609) Nonsyndromic cleft lip ( 31609978) Nose size ( 27182965)
Interacting Genes		1 interacting genes: ALX1	17 interacting genes: ALX4 APCS CLIC3 CREBBP EEF1D EP300 GRP IPO13 KAT5 KRTAP4-4 OR52L1 PACRGL RARA RBM45 SRA1 UROC1 ZNF300
Entrez ID		131669	8092
HPRD ID		08712	03316
Ensembl ID		ENSG00000159650	ENSG00000180318
Uniprot IDs		Q96N76	Q15699 V9HWA7
PDB IDs
Enriched GO Terms of Interacting Partners?
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