COPB1 and FOXB1

Data Source:
BioGRID (two hybrid)

		COPB1	FOXB1
Description		COPI coat complex subunit beta 1	forkhead box B1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Golgi-associated Vesicle Cytosol Plasma Membrane Membrane COPI Vesicle Coat Transport Vesicle Secretory Granule Membrane Intracellular Membrane-bounded Organelle Tertiary Granule Membrane Ficolin-1-rich Granule Membrane	Chromatin Nucleus
	Molecular Function	Structural Molecule Activity Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Viral Process Neutrophil Degranulation	Urogenital System Development Somitogenesis Regulation Of Transcription By RNA Polymerase II Axon Target Recognition Lactation Visual Learning Anatomical Structure Morphogenesis Spinal Cord Development Mammillary Body Development Thalamus Development Hypothalamus Cell Migration Telencephalon Cell Migration Cell Differentiation Midbrain Development Floor Plate Development Negative Regulation Of Neuron Apoptotic Process Epithelial Cell Differentiation Involved In Mammary Gland Alveolus Development Mammillothalamic Axonal Tract Development Mammary Gland Lobule Development Inferior Colliculus Development Cell Migration In Diencephalon
Pathways		Neutrophil degranulation COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		HDL cholesterol ( 26780889) HDL cholesterol levels ( 32203549 28334899) Height ( 31562340) High chromosomal aberration frequency (total) ( 31586183) Vitamin D levels ( 25208829)	Asthma ( 31959851) Night sleep phenotypes ( 27126917)
Interacting Genes		44 interacting genes: ADAM19 APP ARCN1 ARF1 BCAR1 COPE COPG1 COPG2 ERBIN FOXB1 GORAB GRB2 GTPBP4 HLA-DPB1 HLA-G ID1 IRAK3 KCNK3 KDELR1 KIAA1328 LINC00839 LZTS1 LZTS2 NUB1 PDGFRB PRKCE PTEN RGS2 RGS4 RHOQ SCYL1 SERTAD1 SNTA1 SPTBN1 TANK TAPBP TMED10 TRIM37 TTYH2 UBC UBQLN4 VPS18 WBP2 XRCC6	8 interacting genes: COPB1 KRT31 KRT40 KRTAP10-3 KRTAP10-8 NOTCH2NLA PHF5A TRIM27
Entrez ID		1315	27023
HPRD ID		02981	07017
Ensembl ID		ENSG00000129083	ENSG00000171956
Uniprot IDs		P53618	Q99853
PDB IDs
Enriched GO Terms of Interacting Partners?
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