ADH6 and RASSF5

Data Source:
BioGRID (two hybrid)

		ADH6	RASSF5
Description		alcohol dehydrogenase 6 (class V)	Ras association domain family member 5
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Extracellular Exosome	Nucleus Cytoplasm Microtubule
	Molecular Function	Alcohol Dehydrogenase (NAD+) Activity Alcohol Dehydrogenase Activity, Zinc-dependent Retinol Dehydrogenase Activity Zinc Ion Binding	Protein Binding Metal Ion Binding
	Biological Process	Ethanol Oxidation Retinol Metabolic Process Retinoic Acid Metabolic Process Response To Ethanol	Apoptotic Process Signal Transduction Negative Regulation Of Cell Population Proliferation Positive Regulation Of Protein Ubiquitination Intracellular Signal Transduction Regulation Of Apoptotic Process Regulation Of Protein Localization To Nucleus
Pathways		Ethanol oxidation
Drugs
Diseases
GWAS		Alcohol dependence ( 23456092) Alcohol use disorder (consumption score) ( 30940813 30336701) Alcohol use disorder (dependence and problematic use scores) ( 30336701) Esophageal cancer ( 19698717) QRS duration ( 23534349) Regular attendance at a pub or social club ( 29970889)	Inflammatory bowel disease ( 23128233) Late-onset Alzheimer's disease ( 27770636) Neurofibrillary tangles ( 25188341)
Interacting Genes		8 interacting genes: ANKRD17 ARRB1 KRAS RASSF5 RPAIN RPS29 RSL1D1 TNIP1	31 interacting genes: ADH6 AMOTL2 APPBP2 BTRC HRAS ITCH KRAS KRT40 KRTAP4-2 LSM7 MRAS MYLIP NRAS RABIF RALA RAP1B RAP2A RAP2B RASSF1 RASSF2 REL RRAS RRAS2 SMAD4 STK4 TERF2IP TRAF1 TRAF2 UBQLN1 UBQLN2 VPS28
Entrez ID		130	83593
HPRD ID		00067	06117
Ensembl ID		ENSG00000172955	ENSG00000266094
Uniprot IDs		P28332 Q8IUN7	A8K5F3 Q8WWW0
PDB IDs			4LGD 4OH8
Enriched GO Terms of Interacting Partners?
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