COL4A6 and FBLN2

Data Source:
HPRD (in vivo)

		COL4A6	FBLN2
Description		collagen type IV alpha 6 chain	fibulin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Type IV Trimer Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix Collagen-containing Extracellular Matrix	Extracellular Region Extracellular Matrix Collagen-containing Extracellular Matrix Extracellular Vesicle
	Molecular Function	Extracellular Matrix Structural Constituent Protein Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength	Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding Extracellular Matrix Constituent Conferring Elasticity Extracellular Matrix Binding
	Biological Process	Cell Adhesion Extracellular Matrix Organization Collagen-activated Tyrosine Kinase Receptor Signaling Pathway	Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Organization
Pathways		Collagen degradation Collagen degradation Extracellular matrix organization Collagen biosynthesis and modifying enzymes Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions Integrin cell surface interactions Anchoring fibril formation Crosslinking of collagen fibrils Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions ECM proteoglycans Collagen chain trimerization	Molecules associated with elastic fibres Molecules associated with elastic fibres
Drugs
Diseases
GWAS		Electrodermal activity ( 25387706)	Bipolar disorder with mood-incongruent psychosis ( 23092984) Body mass index ( 26426971) Response to cognitive-behavioural therapy in anxiety disorder ( 26989097)
Interacting Genes		12 interacting genes: APP CD93 DCN FBLN2 FN1 HABP2 MAGEA6 MATN2 MMP9 NOTCH1 OSM SERPINE2	30 interacting genes: ACAN ATN1 BCAN COL18A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COL8A1 ELN ERCC6 FBN1 FBXW5 FN1 HSD3B7 HSPG2 ITGB3 JOSD1 LAMA1 LAMA5 LAMC2 LCE3D NID1 OTX1 PRELP VCAN ZNF408 ZNF414
Entrez ID		1288	2199
HPRD ID		02364	00630
Ensembl ID		ENSG00000197565	ENSG00000163520
Uniprot IDs		A0A087WZY5 A8MXH5 A8VPY0 B2RTX6 B7ZMM7 F5H3Q5 Q14031	P98095 Q86V58 Q9Y3V7
PDB IDs
Enriched GO Terms of Interacting Partners?
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