MYOM3 and AMOT

Data Source:
BioGRID (two hybrid)

		MYOM3	AMOT
Description		myomesin 3	angiomotin
Image		No pdb structure
GO Annotations	Cellular Component	M Band	Ruffle Nucleoplasm Cytosol Actin Filament Plasma Membrane Bicellular Tight Junction COP9 Signalosome External Side Of Plasma Membrane Lamellipodium Cell Junction Endocytic Vesicle Cytoplasmic Vesicle
	Molecular Function	Protein Homodimerization Activity Actin Filament Binding	Protein Binding Signaling Receptor Activity Angiostatin Binding
	Biological Process	Muscle Contraction	Angiogenesis Vasculogenesis In Utero Embryonic Development Gastrulation With Mouth Forming Second Establishment Of Cell Polarity Involved In Ameboidal Cell Migration Chemotaxis Negative Regulation Of Angiogenesis Actin Cytoskeleton Organization Regulation Of Cell Migration Negative Regulation Of GTPase Activity Cellular Protein Localization Hippo Signaling Positive Regulation Of Embryonic Development Cell Migration Involved In Gastrulation Blood Vessel Endothelial Cell Migration Regulation Of Small GTPase Mediated Signal Transduction
Pathways
Drugs
Diseases
GWAS		Bipolar disorder with mood-incongruent psychosis ( 23092984) Chronotype ( 30696823) Vigorous physical activity ( 29899525)
Interacting Genes		6 interacting genes: AMOT ASH2L FEM1A GORASP2 NMI RND1	60 interacting genes: ACTA1 AMOTL2 AP1M1 APP AQP1 AXIN2 C1orf216 CAPN3 DISC1 FHL2 HOXA1 HPCAL1 KIAA1328 KRT14 KRT15 KRT16 KRT19 KRT24 KRT27 KRT31 KRT34 KRT36 KRT75 LCE1D LMNB2 LMO4 LURAP1 LZTS1 MAGEA4 MAGI1 MAPK3 MED4 MEOX2 MIS18A MYBPC1 MYBPC2 MYOM3 NEDD4 NEDD4L NF2 NTAQ1 NUFIP2 PBLD PIBF1 PIK3C2A PIN1 PLG PRKAA2 PTEN PTPA PTPN14 RBM48 SEPTIN1 SLIRP SMC1A SNAPC5 SOCS6 THRA TTN UNC119
Entrez ID		127294	154796
HPRD ID		08200	02327
Ensembl ID		ENSG00000142661	ENSG00000126016
Uniprot IDs		Q5VTT5	Q4VCS5
PDB IDs			6JJX
Enriched GO Terms of Interacting Partners?
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