GABPB2 and TSEN2

Data Source:
BioGRID (two hybrid)

		GABPB2	TSEN2
Description		GA binding protein transcription factor subunit beta 2	tRNA splicing endonuclease subunit 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	TRNA-intron Endonuclease Complex Nucleoplasm Nucleolus Centrosome Cytosol
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding Protein Binding	TRNA-intron Endonuclease Activity Nucleic Acid Binding Protein Binding Lyase Activity
	Biological Process	Positive Regulation Of Transcription By RNA Polymerase II	TRNA-type Intron Splice Site Recognition And Cleavage TRNA Splicing, Via Endonucleolytic Cleavage And Ligation MRNA Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways			tRNA processing in the nucleus
Drugs
Diseases			Pontocerebellar hypoplasia
GWAS		Body mass index ( 26426971)	Systemic lupus erythematosus ( 28714469) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		11 interacting genes: CRK GABPA GORASP2 KDM1A LONRF1 PLCG2 RYBP SNRPB2 TSEN2 VAC14 ZDHHC17	7 interacting genes: CADPS CTAG2 GABPB2 RANBP10 TAX1BP1 TEPSIN TSEN54
Entrez ID		126626	80746
HPRD ID		14536	10576
Ensembl ID		ENSG00000143458	ENSG00000154743
Uniprot IDs		Q5SZG2 Q8TAK5	A0A024R2G3 Q8NCE0
PDB IDs
Enriched GO Terms of Interacting Partners?
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