NR2C2AP and NR2C2

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		NR2C2AP	NR2C2
Description		nuclear receptor 2C2 associated protein	nuclear receptor subfamily 2 group C member 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm	Chromatin Nucleoplasm
	Molecular Function	Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Nuclear Receptor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Transcription Initiation From RNA Polymerase II Promoter	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Spermatogenesis Nervous System Development Cell Differentiation Intracellular Receptor Signaling Pathway Positive Regulation Of Embryonic Development Positive Regulation Of Transcription By RNA Polymerase II Anatomical Structure Development
Pathways		Nuclear Receptor transcription pathway	Nuclear Receptor transcription pathway
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Bipolar II disorder ( 31043756)	Alcohol and nicotine co-dependence ( 22488850)
Interacting Genes		7 interacting genes: DDIT4L NR2C2 REL SLC16A3 TCF4 TEPSIN VPS52	23 interacting genes: AR CD2AP CDC37 CHUK ESR1 FKBP5 HDAC4 HNF4A HSP90AA1 HSP90AB1 IKBKB ITSN2 JAZF1 KDM1A NR2C1 NR2C2AP PEBP1 RAC1 RXRB TAB1 TAB2 TRAF2 TRIM55
Entrez ID		126382	7182
HPRD ID		16376	03253
Ensembl ID		ENSG00000184162	ENSG00000177463
Uniprot IDs		Q86WQ0	F2YGU2 P49116
PDB IDs			3P0U
Enriched GO Terms of Interacting Partners?
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