SNX20 and TACC3

Data Source:
BioGRID (two hybrid)

		SNX20	TACC3
Description		sorting nexin 20	transforming acidic coiled-coil containing protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Plasma Membrane Early Endosome Membrane	Spindle Pole Cytoplasm Cytosol Centriolar Satellite Intracellular Membrane-bounded Organelle Mitotic Spindle
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-3-phosphate Binding	Protein Binding
	Biological Process	Protein Transport	Microtubule Cytoskeleton Organization Mitotic Spindle Organization Metaphase/anaphase Transition Of Mitotic Cell Cycle Cell Population Proliferation Cerebral Cortex Development Cell Division Regulation Of Mitotic Spindle Organization Microtubule Cytoskeleton Organization Involved In Mitosis
Pathways			NOTCH3 Activation and Transmission of Signal to the Nucleus Negative regulation of NOTCH4 signaling
Drugs
Diseases
GWAS		Asthma (childhood onset) ( 31036433) Crohn's disease ( 28008999 28067908 22412388) Inflammatory bowel disease ( 28008999 28067908)	Bladder cancer ( 24163127 20972438) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Mean spheric corpuscular volume ( 32888494) Subcortical volume (MOSTest) ( 32665545) Urinary bladder cancer ( 20348956)
Interacting Genes		8 interacting genes: ALAS1 FAM9B GMCL1 KLHL12 MAGEA11 SPDEF TACC3 TFIP11	29 interacting genes: AKAP9 ARHGDIG ARNT ARNT2 ASPSCR1 AURKA BEX2 BEX3 C2CD6 CCHCR1 CDC20B CIB3 CLIP4 EIF3C GDF15 IQCD KAT2A KIZ KLC1 KLHL38 NDEL1 NOD2 NUP54 RNF20 SNX20 SPATA18 TBC1D22B TTF2 VPS37C
Entrez ID		124460	10460
HPRD ID		15401	05601
Ensembl ID		ENSG00000167208	ENSG00000013810
Uniprot IDs		Q7Z614	Q9Y6A5
PDB IDs			5LXN 5LXO 5ODS 5ODT
Enriched GO Terms of Interacting Partners?
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