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TMEM52B and LTC4S
Data Source:
BioGRID
(two hybrid)
TMEM52B
LTC4S
Description
transmembrane protein 52B
leukotriene C4 synthase
Image
No pdb structure
GO Annotations
Cellular Component
Integral Component Of Membrane
Extracellular Exosome
Nuclear Envelope
Nuclear Outer Membrane
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Integral Component Of Membrane
Nuclear Membrane
Intracellular Membrane-bounded Organelle
Molecular Function
Molecular_function
Protein Binding
Glutathione Transferase Activity
Leukotriene-C4 Synthase Activity
Glutathione Peroxidase Activity
Protein Binding
Enzyme Activator Activity
Lipid Binding
Identical Protein Binding
Biological Process
Biological_process
Leukotriene Metabolic Process
Leukotriene Biosynthetic Process
Lipoxygenase Pathway
Long-chain Fatty Acid Biosynthetic Process
Regulation Of Catalytic Activity
Cellular Oxidant Detoxification
Lipoxin Biosynthetic Process
Pathways
Synthesis of 5-eicosatetraenoic acids
Synthesis of Leukotrienes (LT) and Eoxins (EX)
Synthesis of Lipoxins (LX)
Biosynthesis of maresin conjugates in tissue regeneration (MCTR)
Biosynthesis of protectin and resolvin conjugates in tissue regeneration (PCTR and RCTR)
Drugs
Glutathione
Azelastine
Diseases
GWAS
Interacting Genes
68 interacting genes:
ALG3
APOD
APOL2
APOL3
BET1
BTN2A2
C1GALT1
C3orf52
CLDN19
CLDN4
CNIH1
CNIH3
CSGALNACT2
DNAJC30
EMD
FXYD3
GAST
GPR25
GPR37L1
IGFBP5
INSIG2
ITGAM
JAGN1
LHFPL5
LPAR3
LTC4S
MAL
MARCHF2
MIP
MS4A13
NINJ2
NRM
NSG1
ORMDL1
PEDS1-UBE2V1
PGAP2
PLN
PLP1
RTP2
SEC22A
SERP1
SLC30A2
SLC30A8
SLC35A4
SLC35B4
SLC38A7
SMIM1
TF
TMEM100
TMEM107
TMEM109
TMEM128
TMEM147
TMEM14C
TMEM203
TMEM218
TMEM267
TMEM50B
TMEM54
TMEM60
TMEM86B
TMEM97
TMUB2
TRAM1L1
TRARG1
VAMP3
VAMP5
ZDHHC15
12 interacting genes:
ALOX5
ALOX5AP
CD79A
CREB3L1
EBP
FFAR3
FXYD3
GPR152
GPR42
MGST1
SLC7A14
TMEM52B
Entrez ID
120939
4056
HPRD ID
08709
02004
Ensembl ID
ENSG00000165685
ENSG00000213316
Uniprot IDs
Q4KMG9
Q16873
PDB IDs
2PNO
2UUH
2UUI
3B29
3HKK
3LEO
3PCV
4BPM
4J7T
4J7Y
4JC7
4JCZ
4JRZ
4WAB
5HV9
6R7D
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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