CLNS1A and SNRPD3

Data Source:
BioGRID (affinity chromatography technology, two hybrid, two hybrid, two hybrid, two hybrid)

		CLNS1A	SNRPD3
Description		chloride nucleotide-sensitive channel 1A	small nuclear ribonucleoprotein D3 polypeptide
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Cytoskeleton Plasma Membrane Methylosome PICln-Sm Protein Complex	Commitment Complex Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP U7 SnRNP U1 SnRNP U2 SnRNP U4 SnRNP U12-type Spliceosomal Complex Telomerase Holoenzyme Complex Cytosol Nuclear Body Small Nuclear Ribonucleoprotein Complex Methylosome PICln-Sm Protein Complex SMN-Sm Protein Complex U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome Spliceosomal Tri-snRNP Complex
	Molecular Function	RNA Binding Protein Binding	RNA Binding Protein Binding Enzyme Binding Telomerase RNA Binding Histone Pre-mRNA DCP Binding U7 SnRNA Binding
	Biological Process	Spliceosomal SnRNP Assembly Chloride Transport Cell Volume Homeostasis	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription Protein Methylation Histone MRNA Metabolic Process RNA Splicing Import Into Nucleus
Pathways		snRNP Assembly	SLBP independent Processing of Histone Pre-mRNAs snRNP Assembly mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway RNA Polymerase II Transcription Termination SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30224653) Platelet distribution width ( 32888494) Tourette syndrome ( 30818990)	Acne (severe) ( 24927181) Gamma glutamyl transferase levels ( 32084209)
Interacting Genes		17 interacting genes: ACTB CSNK2A1 EIF4A2 EPB41 EPB41L3 FRMD7 ITGA2B LSM10 LSM3 LSM6 PRMT5 SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPG WDR77	27 interacting genes: CASP8 CLNS1A CRY1 DDX20 GEMIN2 GEMIN5 GEMIN6 GEMIN7 IL12RB1 IL7R LSM3 LSM7 NR1I3 NTAQ1 PRMT5 RBL1 SMN1 SMN2 SNRPB SNRPE SNRPG SREK1 STRAP STXBP2 STXBP3 TRDMT1 WDR77
Entrez ID		1207	6634
HPRD ID		03694	03039
Ensembl ID		ENSG00000074201	ENSG00000100028
Uniprot IDs		E9PJF4 E9PMI6 J3KN38 P54105	P62318
PDB IDs		6V0O	1D3B 3CW1 3JCR 3PGW 3VRI 4PJO 4WZJ 5MQF 5O9Z 5XJC 5YZG 5Z56 5Z57 5Z58 6AH0 6AHD 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9 6V4X 6Y53 6Y5Q 7A5P
Enriched GO Terms of Interacting Partners?
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