CLU and PLXNA4

CLU

PLXNA4

Description clusterin plexin A4
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease ( 19734902 19734903 21627779 31473137)
  • Alzheimer's disease (late onset) ( 21460841 30617256 24162737 28714976)
  • Alzheimer's disease in APOE e4+ carriers ( 25778476)
  • Alzheimer's disease in APOE e4- carriers ( 25778476)
  • Alzheimer's disease or family history of Alzheimer's disease ( 30617256)
  • Alzheimer's disease or fasting insulin levels (pleiotropy) ( 30805717)
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Family history of Alzheimer's disease ( 30617256)
  • Lung adenocarcinoma ( 28604730)
  • Lung cancer in ever smokers ( 28604730)
  • Panic disorder ( 19165232)
  • Refractive error ( 32231278)
  • Schizophrenia ( 25056061 29483656)
  • Smoking behaviour (cigarettes smoked per day) ( 31089300)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027)
  • Age-related hearing impairment ( 24939585)
  • Bipolar disorder ( 31043756)
  • Bone mineral density (femoral neck) in inflammatory bowel disease ( 29603369)
  • Chronotype ( 30696823)
  • Cognitive function ( 24684796)
  • Diastolic blood pressure ( 27841878)
  • Economic and political preferences ( 22566634)
  • Fractures (paediatric) ( 32742401)
  • Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828)
  • Oleic acid (18:1n-9) levels ( 23362303)
  • Refractive error ( 32231278)
  • Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)
  • Self-employment ( 23593239)
  • Systolic blood pressure ( 27841878)
Interacting Genes 50 interacting genes: APP BAG6 C7 C8B C9 CBY1 CD209 CLUAP1 CYP2E1 DISC1 ELN EPPIN FOS GRB2 HSPD1 IL24 KATNA1 KEAP1 KLF11 KNSTRN LEP LEPR LIG4 LRP2 LRP8 LYZ MAPK9 MDM2 MMP25 MSRB1 PAXIP1 PLXNA4 POLR1C PON1 PRNP RBBP8 RPL23 SRPK2 SYVN1 TGFBR1 TGFBR2 TNIK TREM2 TSC22D4 TTR UBC VHL VLDLR XRCC6 ZWINT 1 interacting genes: CLU
Entrez ID 1191 91584
HPRD ID 01706 10901
Ensembl ID ENSG00000120885 ENSG00000221866
Uniprot IDs P10909 A0A024R7A6 Q9HCM2
PDB IDs 4E74
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?