ZFYVE27 and PIP4P2

Data Source:
BioGRID (two hybrid)

		ZFYVE27	PIP4P2
Description		zinc finger FYVE-type containing 27	phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Cytosol Integral Component Of Endoplasmic Reticulum Membrane Axon Dendrite Growth Cone Membrane Intracellular Membrane-bounded Organelle Recycling Endosome Membrane Endoplasmic Reticulum Tubular Network	Lysosomal Membrane Plasma Membrane Integral Component Of Membrane Phagocytic Vesicle Membrane Late Endosome Membrane
	Molecular Function	Protein Binding Identical Protein Binding Protein Self-association Metal Ion Binding	Protein Binding Phosphatidylinositol-4,5-bisphosphate 4-phosphatase Activity
	Biological Process	Vesicle-mediated Transport Neuron Projection Development Positive Regulation Of Axon Extension Neurotrophin TRK Receptor Signaling Pathway Endoplasmic Reticulum Tubular Network Formation Protein Localization To Plasma Membrane	Phosphatidylinositol Dephosphorylation Negative Regulation Of Phagocytosis
Pathways
Drugs
Diseases		Hereditary spastic paraplegia (SPG)
GWAS
Interacting Genes		18 interacting genes: APP GIMAP1 GIMAP5 IER3IP1 ORMDL1 OTOP3 PIP4P2 SACM1L SEC22A SLC30A8 SLC66A2 STX7 TMEM128 TMEM14C TMEM243 TMEM65 TSPAN2 YIF1A	5 interacting genes: GTF2IRD1 NEDD4L SLC10A6 TNF ZFYVE27
Entrez ID		118813	55529
HPRD ID		15735	13233
Ensembl ID		ENSG00000155256	ENSG00000155099
Uniprot IDs		A0A0S2Z627 B7Z6J9 Q5T4F4	Q8N4L2
PDB IDs		1X4U
Enriched GO Terms of Interacting Partners?
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