AGAP1 and ARF6

  • Data Source:
  • BioGRID (enzymatic study)

AGAP1

ARF6

Description ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 ADP ribosylation factor 6
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Aspartate aminotransferase levels in non-alcoholic fatty liver disease ( 31311600)
  • Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444)
  • Craniofacial microsomia ( 26853712)
  • Mean corpuscular hemoglobin ( 29403010)
  • Mean corpuscular volume ( 29403010)
  • Menarche (age at onset) ( 23667675)
  • Venlafaxine response in generalised anxiety disorder (responders vs non-responders after 24 weeks) ( 28437668)
  • Erythema nodosum in inflammatory bowel disease ( 24487271)
Interacting Genes 14 interacting genes: APP ARF1 ARF6 CDC42 GRB7 GUCY1A1 GUCY1B1 RAC1 RHOA RSPH14 SMN1 SRC TK1 ZNF534 37 interacting genes: AGAP1 AP1B1 AP3B1 AP3D1 AP3S2 APBB1 APP ARFIP2 ARHGAP10 ARRB1 ARRB2 ASAP1 ASAP2 ASAP3 ATP6V0C CAPN1 CHRM3 CYTH1 CYTH2 EXOC5 EZR HTR2A IKBKG ITSN1 MEOX2 MT2A PALS1 PIP5K1A PIP5K1C PLD1 RAB11A RAB11FIP3 RAB11FIP4 RAB11FIP5 SMAP1 SPAG9 ZNF709
Entrez ID 116987 382
HPRD ID 16359 02714
Ensembl ID ENSG00000157985 ENSG00000165527
Uniprot IDs B2RZG9 Q9UPQ3 X5D293 P62330
PDB IDs 1E0S 2A5D 2A5F 2A5G 2BAO 2BAU 2J5X 2W83 3LVQ 3LVR 3N5C 3PCR 4FME 4KAX 6BBP 6BBQ 6PAU
Enriched GO Terms of Interacting Partners?
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