PHACTR3 and PLPP6

Data Source:
BioGRID (two hybrid)

		PHACTR3	PLPP6
Description		phosphatase and actin regulator 3	phospholipid phosphatase 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nuclear Matrix	Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Actin Binding Protein Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase 1 Binding	Protein Binding Hydrolase Activity Sphingosine-1-phosphate Phosphatase Activity Lipid Phosphatase Activity
	Biological Process	Actin Cytoskeleton Organization Negative Regulation Of Phosphoprotein Phosphatase Activity	Cholesterol Biosynthetic Process Phospholipid Dephosphorylation
Pathways			Cholesterol biosynthesis
Drugs
Diseases
GWAS		Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Refractive error ( 32231278) Rheumatoid arthritis ( 30891314) Schizophrenia ( 30285260)
Interacting Genes		10 interacting genes: CAPNS2 CYB5B EEF1G MAPK6 PLPP6 PPP1CA PPP1CB TAB1 UBIAD1 UBL5	57 interacting genes: AMIGO1 AQP6 AQP8 BTN2A1 BTNL9 C16orf92 CD79A CIAO2A CLDN15 CLDN9 CLEC4M CLN5 COMT CREB3L1 EBP FAM174A FAM209A FAM210B FKBP7 FNDC9 FXYD3 GJB5 GKN1 GORAB GPX8 HSH2D IL10RA IL13RA2 KASH5 LAYN LDLRAD1 MMGT1 MS4A3 MUC1 NCR3LG1 PDGFRA PDZK1IP1 PHACTR3 PRLR PVR RETREG3 RNF170 RNF5 SEC11C SHISAL1 SIGLEC12 SLC7A14 SMAGP SOCS4 SSMEM1 STX1A SYNE4 SYNPR TMEM106C TMIE TNFRSF10D VSIR
Entrez ID		116154	403313
HPRD ID		10571	17397
Ensembl ID		ENSG00000087495	ENSG00000205808
Uniprot IDs		B7Z339 Q96KR7	Q8IY26
PDB IDs
Enriched GO Terms of Interacting Partners?
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