RAB3C and RIMS2

Data Source:
HPRD (in vitro)

		RAB3C	RIMS2
Description		RAB3C, member RAS oncogene family	regulating synaptic membrane exocytosis 2
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Cytosol Plasma Membrane Synaptic Vesicle Vesicle Perinuclear Region Of Cytoplasm Anchored Component Of Synaptic Vesicle Membrane	Presynaptic Membrane Cell Projection Presynaptic Active Zone Cytoskeleton Of Presynaptic Active Zone Extracellular Exosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding GTP-dependent Protein Binding Myosin V Binding	Protein Binding Ion Channel Binding Metal Ion Binding
	Biological Process	Vesicle Docking Involved In Exocytosis Protein Secretion Regulation Of Exocytosis Antigen Processing And Presentation Protein Localization To Plasma Membrane	Intracellular Protein Transport Positive Regulation Of Gene Expression Calcium-ion Regulated Exocytosis Regulation Of Exocytosis CAMP-mediated Signaling Insulin Secretion Cell Differentiation Regulation Of Membrane Potential Regulation Of Synaptic Plasticity Calcium Ion-regulated Exocytosis Of Neurotransmitter Positive Regulation Of Synaptic Transmission Spontaneous Neurotransmitter Secretion Positive Regulation Of Inhibitory Postsynaptic Potential Positive Regulation Of Dendrite Extension Regulation Of Synaptic Vesicle Exocytosis Positive Regulation Of Excitatory Postsynaptic Potential
Pathways		RAB geranylgeranylation
Drugs
Diseases
GWAS		Breast cancer ( 29059683 23535729) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Hippocampal volume ( 25625606) Metabolite levels ( 23823483) Perceived intensity of sweet substances ( 31005972) Sleep duration (long sleep) ( 30846698)	Cocaine dependence ( 23958962) Dietary fat liking ( 32516399) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) High density lipoprotein cholesterol levels ( 30498476) Monoclonal gammopathy of undetermined significance ( 30737484) Multiple system atrophy (pathologically confirmed) ( 27629089)
Interacting Genes		5 interacting genes: FKBP2 RABIF RIMS2 RPH3AL VRTN	12 interacting genes: ABCA1 CACNA1S RAB27A RAB3A RAB3B RAB3C RAB3D RAB8A RABAC1 RAPGEF4 RPH3AL YWHAH
Entrez ID		115827	9699
HPRD ID		06704	09436
Ensembl ID		ENSG00000152932	ENSG00000176406
Uniprot IDs		Q96E17	Q9UQ26
PDB IDs			1V27 1WFG
Enriched GO Terms of Interacting Partners?
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