EVI5L and GAS8

Data Source:
BioGRID (two hybrid)

		EVI5L	GAS8
Description		ecotropic viral integration site 5 like	growth arrest specific 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Golgi Apparatus Cytosol Microtubule Plasma Membrane Cilium Axoneme Motile Cilium Ciliary Basal Body
	Molecular Function	GTPase Activator Activity Protein Binding Small GTPase Binding	Molecular_function Protein Binding Microtubule Binding
	Biological Process	Intracellular Protein Transport Positive Regulation Of GTPase Activity Activation Of GTPase Activity Negative Regulation Of Cilium Assembly	Negative Regulation Of Cell Population Proliferation Flagellated Sperm Motility Cellular Protein Localization Axoneme Assembly Positive Regulation Of Smoothened Signaling Pathway Cilium Movement Involved In Cell Motility Positive Regulation Of Protein Localization To Cilium Regulation Of Microtubule Binding
Pathways			Activation of SMO
Drugs
Diseases
GWAS		HIV-1 viral setpoint ( 20205591) Menarche (age at onset) ( 25231870)	Brain morphology (MOSTest) ( 32665545)
Interacting Genes		15 interacting genes: A2M ANKRD36 AP1M1 CCDC185 GAS8 KRT79 LNX1 NUDT18 PRPF18 PSEN2 RAB10 RBM7 SRPK2 TBC1D21 ZNF648	111 interacting genes: ARL6IP1 BCAR3 BHLHB9 BORCS6 BYSL C1orf35 CARD10 CARD9 CBFA2T3 CCDC125 CCDC146 CCDC6 CCHCR1 CCNG1 CDC37 CDR2 CEP70 CFAP53 CINP CKS1B COG6 CPSF7 CRYBB1 CT45A1 CWF19L2 CYSRT1 DAXX DDX17 DISC1 DMAP1 EAF1 EHHADH EIF1AD ERCC1 EVI5L FAM161A FAM161B FHL2 GADD45GIP1 GCC1 GEM GOLGA2 GRIPAP1 GSTA4 HEXIM2 HOMER3 HOMEZ HOXA1 HSF2BP IGFBP6 KDM1A KRT14 KRT15 KRT16 KRT27 L3MBTL2 L3MBTL3 LASP1 LHX3 LMO1 LMO2 LZTS1 MAD1L1 MFAP1 MID2 MRFAP1L1 NDOR1 NKAPD1 PLK4 PNKP PNMA5 POLR1C POTEB3 PPFIA1 PRDM14 PRMT5 PRPF18 RALBP1 RBAK RINT1 RUBCN SCNM1 SKIL SORBS3 SP7 SPATA18 SPG21 STAC3 TCEA2 THAP1 TNFAIP3 TRAF2 TRAF5 TRIM41 TRIM54 TSFM TSGA10IP TXLNA TXLNB USHBP1 YES1 YJU2 ZBTB22 ZBTB26 ZBTB39 ZNF212 ZNF250 ZNF572 ZNF620 ZNF629 ZNF792
Entrez ID		115704	2622
HPRD ID		10044	05533
Ensembl ID		ENSG00000142459	ENSG00000141013
Uniprot IDs		A0A384MR55 Q96CN4	A0A087WZT7 A0A384MR00 B7Z1U9 O95995
PDB IDs
Enriched GO Terms of Interacting Partners?
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