FMNL2 and MIPOL1

Data Source:
BioGRID (two hybrid)

		FMNL2	MIPOL1
Description		formin like 2	mirror-image polydactyly 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol	Nucleus
	Molecular Function	Cadherin Binding Actin Filament Binding	Protein Binding Identical Protein Binding
	Biological Process	Cytoskeleton Organization Regulation Of Cell Shape Cell Migration Regulation Of Cell Morphogenesis Cortical Actin Cytoskeleton Organization
Pathways		RHO GTPases Activate Formins
Drugs
Diseases
GWAS		Asthma (childhood onset) ( 27611488) Corneal astigmatism ( 30306274) Glaucoma ( 30054594) Glaucoma (primary open-angle) ( 29891935) Heel bone mineral density ( 30598549) Intraocular pressure ( 29617998 29785010 31959993 30054594 29235454) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Refractive astigmatism ( 30306274) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) White blood cell count ( 32888494)	Eosinophil percentage of white cells ( 32888494) Estimated glomerular filtration rate ( 31152163) Intraocular pressure ( 29617998) Longitudinal alcohol consumption ( 26081443) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Mean reticulocyte volume ( 32888494) Metabolite levels ( 23823483) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Red blood cell count ( 32888494) Tonsillectomy ( 27182965 28928442)
Interacting Genes		12 interacting genes: AP1B1 AP2B1 APP CCDC197 CDC42 KRT27 MIPOL1 NECAB1 PNMA1 PRPF40A SUOX TXN2	73 interacting genes: ANKRD23 ARNT2 ATP5PO BEX2 BYSL C1orf109 C1orf35 C2CD6 CCDC120 CCDC146 CCDC33 CCT3 CDC37 CDK18 CKS1B DAXX DGCR6 EAF1 EIF4E2 ENKD1 EXOC8 FAM124B FAM161A FAM161B FAM90A1 FBF1 FMNL2 GADD45GIP1 GEM HAUS1 KDF1 KIF9 LAGE3 LENG1 MAGEA6 MBD3 MCM7 MFAP1 MOS MYLIP NEBL NTAQ1 PAX6 PBX4 PKN1 PPP1R13B PRDM16 PRPF31 RBM41 RCOR3 REL RIIAD1 RNF6 RTP5 SCNM1 SMARCE1 SNAP91 SNTG2 SRPK2 SSX3 STMN3 TBC1D7 TCHP TSEN15 TSGA10IP TTC12 TXN2 UBE2I UBE2K USH1C UTP25 ZGPAT ZNF688
Entrez ID		114793	145282
HPRD ID		13545	06029
Ensembl ID		ENSG00000157827	ENSG00000151338
Uniprot IDs		Q96PY5	A8K735 G5EA54 Q4G0U7 Q8TD10
PDB IDs		4YC7
Enriched GO Terms of Interacting Partners?
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