MAL2 and NFAM1

Data Source:
BioGRID (two hybrid)

		MAL2	NFAM1
Description		mal, T cell differentiation protein 2	NFAT activating protein with ITAM motif 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endomembrane System Integral Component Of Membrane Apical Plasma Membrane Membrane Raft Perinuclear Region Of Cytoplasm Extracellular Exosome	Plasma Membrane Integral Component Of Membrane Azurophil Granule Membrane Membrane Raft
	Molecular Function	Protein Binding Structural Constituent Of Myelin Sheath	Transmembrane Signaling Receptor Activity Protein Binding
	Biological Process	Myelination Transcytosis	Positive Regulation Of Cytokine Production Inflammatory Response Signal Transduction B Cell Differentiation Intracellular Signal Transduction Neutrophil Degranulation Regulation Of B Cell Differentiation B Cell Receptor Signaling Pathway Positive Regulation Of B Cell Receptor Signaling Pathway Positive Regulation Of DNA-binding Transcription Factor Activity
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS		Blood pressure (smoking interaction) ( 25189868) Gallstone disease ( 30504769) Hippocampal atrophy ( 19668339) Osteoprotegerin levels ( 25080503)	Chronotype ( 30696823) Machado-Joseph disease (age at onset) ( 32205469) Refractive error ( 32231278) Risk-taking tendency (4-domain principal component model) ( 30643258)
Interacting Genes		49 interacting genes: ABCG8 AQP6 ARFIP2 ARL13B ATP6V0E1 CD160 CD68 COQ8A CREB3 CREB3L1 ECPAS FAM3A GAD1 GAD2 GJB1 GPR152 HSFX1 HSFX2 MRM1 MTERF3 MUC1 NDRG4 NFAM1 PBX3 PIMREG PITPNC1 POLL PPP1CA PTPN9 RAB37 REEP4 RETREG3 S100B SCN3B SGK1 SH3GL1 SH3GLB1 SHMT2 SLC35C2 SUCLA2 TBRG4 THAP4 TMEM14B TPD52 TPD52L1 TPD52L2 TTPA TUBB VARS2	5 interacting genes: BCL11A MAL2 SYK TCF4 ZAP70
Entrez ID		114569	150372
HPRD ID		14351	16380
Ensembl ID		ENSG00000147676	ENSG00000235568
Uniprot IDs		A0A024R9E4 Q969L2	Q8NET5
PDB IDs
Enriched GO Terms of Interacting Partners?
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