LYST and MRPL17

Data Source:
HPRD (two hybrid)

		LYST	MRPL17
Description		lysosomal trafficking regulator	mitochondrial ribosomal protein L17
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Microtubule Cytoskeleton Membrane	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Large Ribosomal Subunit Large Ribosomal Subunit
	Molecular Function	Protein Binding Protein Kinase Binding	Structural Constituent Of Ribosome Protein Binding Protein Domain Specific Binding
	Biological Process	Phagocytosis Lysosome Organization Protein Localization Protein Transport Leukocyte Chemotaxis Melanosome Organization Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Mast Cell Secretory Granule Organization Natural Killer Cell Mediated Cytotoxicity Defense Response To Bacterium Defense Response To Protozoan Pigmentation Defense Response To Virus	Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways			Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs
Diseases		Other phagocyte defects, including the following eight diseases: Chediak-Higashi syndrome; Griscelli syndrome, type 1 (GS1); Griscelli syndrome, type 2 (GS2); Griscelli syndrome, type 3 (GS3); beta-actin deficiency; Neutrophil-specific granule deficiency; Myeloperoxidase deficiency; Glucose 6-phosphate dehydrogenase deficiency; Shwachman syndrome
GWAS		Basophil percentage of white cells ( 32888494) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Post bronchodilator FEV1/FVC ratio ( 26634245) Systemic lupus erythematosus ( 26502338 19838195)	Malaria ( 31844061)
Interacting Genes		24 interacting genes: ATN1 CALM1 CELF4 CENPJ CNTROB CSNK2B DNAJC14 EFS ESRRA ESS2 HGS HNRNPM KPNB1 MED12 MRPL17 MRPS31 NCDN PCBP4 TNNI3 VTA1 YWHAB YWHAQ YWHAZ ZNF521	3 interacting genes: HNRNPF LYST UBTD2
Entrez ID		1130	63875
HPRD ID		06060	10096
Ensembl ID		ENSG00000143669	ENSG00000158042
Uniprot IDs		Q99698	Q9NRX2
PDB IDs			2CQM 3J7Y 3J9M 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG
Enriched GO Terms of Interacting Partners?
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