PNKP and XRCC4

  • Data Source:
  • HPRD (in vitro, in vivo)

PNKP

XRCC4

Description polynucleotide kinase 3'-phosphatase X-ray repair cross complementing 4
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Clozapine-induced agranulocytosis ( 25187353)
  • Diisocyanate-induced asthma ( 25918132)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Heel bone mineral density ( 30598549)
  • Osteoarthritis biomarkers ( 25057126)
  • Squamous cell lung carcinoma ( 28604730)
  • Type 2 diabetes ( 25760438)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
  • White matter integrity (fractional anisotropy) ( 29752348)
  • White matter integrity (mean diffusivity) ( 29752348)
Interacting Genes 49 interacting genes: APP CACFD1 CAMK2B CARD10 CCDC14 CCDC43 CISD2 CNTROB COL17A1 DVL3 FADS6 GAS8 GZMK IKZF1 KANK2 KDM1A KLHL12 KRTAP4-12 LMNA MAGEA11 MCC MEOX2 MGST2 MSANTD4 MYOZ1 OBI1 PICK1 PNMA5 POLB PSTPIP1 RPRM SFT2D1 SMAD5 SNX2 SP4 SUV39H1 SYNGR1 SYNGR3 SYP TARBP2 TBC1D1 THAP1 TMEM239 TNIP1 TRIM37 XRCC1 XRCC4 ZBTB14 ZNF639 23 interacting genes: ACTN1 AHNAK APLF APTX ASTE1 BIN1 CAAP1 CALM1 CHD3 CSNK2A1 FAM9B GSC2 GZMB HAUS2 IFFO1 KRT27 LIG4 MAGEA6 NBN NHEJ1 PNKP PRKDC VIM
Entrez ID 11284 7518
HPRD ID 09284 15951
Ensembl ID ENSG00000039650 ENSG00000152422
Uniprot IDs Q96T60 A0A024RAL0 A0A024RAP0 A0A024RAQ8 Q13426 Q7Z763
PDB IDs 2BRF 2W3O 1FU1 1IK9 3II6 3MUD 3Q4F 3RWR 3SR2 3W03 4XA4 5CHX 5CJ0 5CJ4 5E50 5WJ7 5WLZ 6ABO
Enriched GO Terms of Interacting Partners?
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