SYNRG and CCDC91

Data Source:
HPRD (in vitro)

		SYNRG	CCDC91
Description		synergin gamma	coiled-coil domain containing 91
Image
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus AP-1 Adaptor Complex Clathrin Coat Of Trans-Golgi Network Vesicle	Nucleoplasm Golgi Apparatus Trans-Golgi Network Cytosol Membrane
	Molecular Function	Protein Binding	Identical Protein Binding
	Biological Process	Intracellular Protein Transport Endocytosis	Protein Transport Golgi To Lysosome Transport
Pathways
Drugs
Diseases
GWAS		Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Ovarian cancer ( 23535730) Response to angiotensin II receptor blocker therapy ( 22566498)	Adverse response to drug ( 30420678) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Bone ultrasound measurement (velocity of sound) ( 28472463) Brain morphology (MOSTest) ( 32665545) Breast size ( 27182965) Chronic obstructive pulmonary disease ( 30804561) FEV1 ( 30804560) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Heel bone mineral density ( 30598549) Height ( 28552196 20881960 25282103 23563607 31562340) High light scatter reticulocyte count ( 32888494) Hip circumference adjusted for BMI ( 25673412) Immature fraction of reticulocytes ( 32888494) Lumbar spine bone mineral density (trabecular) ( 27476799) Lung function (FEV1) ( 28166213 26635082) Lung function (FVC) ( 28166213 26635082 30804560) Lung function (low FEV1 vs high FEV1) ( 26423011) Lung function in never smokers (low FEV1 vs high FEV1) ( 26423011) Narrowest width of the femoral neck ( 30888730) Obesity-related traits ( 23251661) Ossification of the posterior longitudinal ligament of the spine ( 25064007) Osteoarthritis of the hand ( 28855172) Peak expiratory flow ( 30804560) Reticulocyte fraction of red cells ( 32888494) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 25673412 28448500)
Interacting Genes		8 interacting genes: AP1G1 AP1G2 APPBP2 CCDC91 GGA1 GGA2 GGA3 SCAMP1	11 interacting genes: AP1G1 CDC37 DAPK2 ECT2 EWSR1 GGA1 GGA2 LNX1 PRR5L SYNRG TESC
Entrez ID		11276	55297
HPRD ID		06291	16905
Ensembl ID		ENSG00000275066	ENSG00000123106
Uniprot IDs		Q9UMZ2	A0A024RAW6 Q05D28 Q7Z6B0
PDB IDs		2MX7	1OM9
Enriched GO Terms of Interacting Partners?
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