MAP4K1 and TMEM101

		MAP4K1	TMEM101
Description		mitogen-activated protein kinase kinase kinase kinase 1	transmembrane protein 101
Image			No pdb structure
GO Annotations	Cellular Component	Membrane	Cellular_component Integral Component Of Membrane
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding MAP Kinase Kinase Kinase Kinase Activity Protein Serine Kinase Activity Protein Threonine Kinase Activity	Protein Binding
	Biological Process	Activation Of MAPKKK Activity Protein Phosphorylation Activation Of JUN Kinase Activity Cell Population Proliferation Peptidyl-serine Phosphorylation Protein Autophosphorylation Cellular Response To Phorbol 13-acetate 12-myristate	Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Pathways
Drugs		Fostamatinib
Diseases
GWAS		Diisocyanate-induced asthma ( 25918132)
Interacting Genes		22 interacting genes: ABL1 BLNK CARD11 CASP3 CRK CRKL DAPP1 DBNL EGFR GRAP2 GRB2 H2AC4 HCLS1 LAT LCP2 LYN MAP3K11 MAP3K7 NCK1 SHC1 SYK TMEM101	21 interacting genes: BNIP3 C4orf3 CCR4 DRD2 GIMAP1 GPR182 MAP4K1 NDUFA3 NINJ2 NPSR1 PDZK1IP1 PKMYT1 STRIT1 STX10 SYNJ2BP TMEM243 TMEM65 TMIE VAMP1 VAMP2 VAPB
Entrez ID		11184	84336
HPRD ID		03583	14623
Ensembl ID		ENSG00000104814	ENSG00000091947
Uniprot IDs		Q92918	B4DFS4 Q96IK0
PDB IDs		6CQD 6CQE 6CQF 6NFY 6NFZ 6NG0
Enriched GO Terms of Interacting Partners?
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