WDR6 and GRIP1

Data Source:
BioGRID (two hybrid)

		WDR6	GRIP1
Description		WD repeat domain 6	glutamate receptor interacting protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane COP9 Signalosome	Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Postsynaptic Density Dendrite Cytoplasmic Vesicle Neuron Projection Perikaryon Membrane Raft Postsynaptic Membrane Glutamatergic Synapse
	Molecular Function	RNA Binding Protein Binding	Protein Binding Beta-catenin Binding Protein C-terminus Binding Signaling Receptor Complex Adaptor Activity Glucocorticoid Receptor Binding
	Biological Process	Cell Cycle Arrest Negative Regulation Of Cell Population Proliferation Negative Regulation Of Autophagy	Dendrite Development Intracellular Signal Transduction Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Vesicle-mediated Transport In Synapse Positive Regulation Of Neuron Projection Arborization
Pathways			Trafficking of GluR2-containing AMPA receptors
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Menarche (age at onset) ( 25231870) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)	Basophil percentage of granulocytes ( 27863252) Basophil percentage of white cells ( 27863252) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		5 interacting genes: BRCA1 CDC42EP4 G2E3 GRIP1 PTPN3	42 interacting genes: AGAP2 AR CARM1 CSPG4 DEPDC1B DZIP3 EEPD1 EFNA5 EFNB1 EFNB2 EP300 ESR1 FGF12 FLII GPR37 GRIA1 GRIA3 GRIA4 GRIK1 GRIK2 GRIPAP1 GRM2 GRM3 GRM7 H3C1 HUS1 IRF3 MFAP3 NCOA6 NEK6 NR3C1 NUMBL PICK1 PPARG PRKD2 PRMT1 RXRA THRA UBE2I VDR WDR6 XDH
Entrez ID		11180	23426
HPRD ID		06912	19086
Ensembl ID		ENSG00000178252	ENSG00000155974
Uniprot IDs		A0A087X295 B3KRR8 B4E256 E9PDU5 Q9H9M3 Q9NNW5	Q9Y3R0
PDB IDs			2JIL
Enriched GO Terms of Interacting Partners?
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