PSIP1 and HCFC1

Data Source:
HPRD (in vitro)

		PSIP1	HCFC1
Description		PC4 and SFRS1 interacting protein 1	host cell factor C1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Transcriptionally Active Chromatin	Histone Acetyltransferase Complex Nucleus Nucleoplasm Ada2/Gcn5/Ada3 Transcription Activator Complex Cytoplasm Membrane Protein-containing Complex Histone Methyltransferase Complex Neuronal Cell Body Set1C/COMPASS Complex SAGA-type Complex MLL1 Complex
	Molecular Function	Double-stranded DNA Binding Transcription Coregulator Activity RNA Binding Protein Binding Supercoiled DNA Binding	Chromatin Binding Transcription Coactivator Activity Protein Binding Protein-macromolecule Adaptor Activity Activating Transcription Factor Binding Identical Protein Binding Cadherin Binding
	Biological Process	MRNA 5'-splice Site Recognition Regulation Of Transcription By RNA Polymerase II Response To Oxidative Stress Response To Heat Nuclear Transport Establishment Of Integrated Proviral Latency	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Remodeling Regulation Of Transcription, DNA-templated Mitochondrion Organization Cell Cycle Positive Regulation Of Gene Expression Protein Deubiquitination Release From Viral Latency Regulation Of Protein-containing Complex Assembly Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K16 Acetylation Positive Regulation Of Cell Cycle Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Protein Stabilization
Pathways		Integration of provirus 2-LTR circle formation Integration of viral DNA into host genomic DNA Autointegration results in viral DNA circles APOBEC3G mediated resistance to HIV-1 infection Vpr-mediated nuclear import of PICs	Transcriptional activation of mitochondrial biogenesis HATs acetylate histones UCH proteinases
Drugs
Diseases
GWAS			Celiac disease ( 22057235) Rheumatoid arthritis ( 23143596) Rheumatoid arthritis (ACPA-positive) ( 23143596) Systemic lupus erythematosus ( 26502338)
Interacting Genes		13 interacting genes: CASP3 CASP7 CDC42 CSNK2A1 HCFC1 HMGA1 HMGA2 MAPK6 MTDH SP1 SRSF1 SUB1 SUMO1	33 interacting genes: ASF1B CLP1 CREB3 CREBZF E2F1 E2F3 E2F4 EGR2 FOXK2 GABPA GABPB1 HCFC1R1 HSPA1A JUN KMT2A MED25 NFE2L1 OGT PDCD2 POU2F1 PPARGC1A PPARGC1B PPP1CC PSIP1 SETD7 SIN3A SP1 SUMO2 TAF9 THAP11 THAP7 YY1 ZBTB17
Entrez ID		11168	3054
HPRD ID		04688	02061
Ensembl ID		ENSG00000164985	ENSG00000172534
Uniprot IDs		O75475	A6NEM2 P51610
PDB IDs		1Z9E 2B4J 2M16 2MSR 2MTN 2N3A 3F9K 3HPG 3HPH 3U88 3ZEH 4FU6 5N88 5OYM 5YI9 6EMO 6EMP 6EMQ 6EMR 6S01 6TRJ 6TVM 6Z2Y	4GO6 4N39 4N3A 4N3B 4N3C 5LWV 6MA1 6MA2 6MA3 6MA4 6MA5
Enriched GO Terms of Interacting Partners?
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