KIF3A and KIF3B

Data Source:
HPRD (in vitro, in vivo)

		KIF3A	KIF3B
Description		kinesin family member 3A	kinesin family member 3B
Image		No pdb structure
GO Annotations	Cellular Component	Centrosome Centriole Cytosol Kinesin Complex Microtubule Spindle Microtubule Cilium Microtubule Cytoskeleton Kinesin II Complex Extracellular Exosome Ciliary Tip Axon Cytoplasm	Centrosome Cytosol Kinesin Complex Plus-end Kinesin Complex Microtubule Spindle Microtubule Cilium Microtubule Cytoskeleton Membrane Kinesin II Complex Midbody Extracellular Exosome Ciliary Tip Axon Cytoplasm
	Molecular Function	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity Protein Phosphatase Binding Spectrin Binding Small GTPase Binding	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity Small GTPase Binding Intraciliary Transport Particle B Binding
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Organelle Organization Microtubule-based Movement Anterograde Axonal Transport Centriole-centriole Cohesion Protein Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Microtubule Anchoring At Centrosome Intraciliary Transport Involved In Cilium Assembly Cilium Assembly Plus-end-directed Vesicle Transport Along Microtubule Protein Localization To Cell Junction	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Mitotic Spindle Organization Mitotic Centrosome Separation Determination Of Left/right Symmetry Anterograde Axonal Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Positive Regulation Of Cytokinesis Intraciliary Transport Involved In Cilium Assembly Plus-end-directed Vesicle Transport Along Microtubule Mitotic Spindle Assembly
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane MHC class II antigen presentation Hedgehog 'off' state Intraflagellar transport Activation of SMO Activation of SMO COPI-dependent Golgi-to-ER retrograde traffic Kinesins Kinesins	Translocation of SLC2A4 (GLUT4) to the plasma membrane MHC class II antigen presentation Intraflagellar transport COPI-dependent Golgi-to-ER retrograde traffic Kinesins Kinesins
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Asthma ( 31959851 31619474) Asthma (childhood onset) ( 31036433) Asthma or allergic disease (pleiotropy) ( 29785011) Atopic dermatitis ( 23042114 25574825 22197932 26482879) Atopic march ( 26542096) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Mosquito bite size ( 28199695) Refractive error ( 32231278)	Age at first sexual intercourse ( 27089180) Chronic obstructive pulmonary disease ( 28166215) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Granulocyte percentage of myeloid white cells ( 27863252) Inflammatory bowel disease ( 28067908) Monocyte percentage of white cells ( 27863252)
Interacting Genes		15 interacting genes: APP DISC1 GRB2 KIF3B KIF3C LIG4 MAP3K10 MAP3K11 NEK1 PLEKHA5 PPP1R15A RPGR TRIM14 TULP3 VHL	12 interacting genes: APP IFT20 KIF3A KIFAP3 LMO2 LMO4 MAP3K10 MAP3K11 NEDD4L PRC1 RAB4A SASH1
Entrez ID		11127	9371
HPRD ID		05250	04781
Ensembl ID		ENSG00000131437	ENSG00000101350
Uniprot IDs		B4DHG8 E9PES4 J3KPF9 Q05CT3 Q9Y496	O15066
PDB IDs			3B6U
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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