PRDM4 and DAO

Data Source:
BioGRID (affinity chromatography technology)

		PRDM4	DAO
Description		PR/SET domain 4	D-amino acid oxidase
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GO Annotations	Cellular Component	Nucleus Cytoplasm Histone Methyltransferase Complex	Cytoplasm Mitochondrial Outer Membrane Peroxisome Peroxisomal Membrane Peroxisomal Matrix Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Methyltransferase Activity Metal Ion Binding Histone Methyltransferase Binding Sequence-specific Double-stranded DNA Binding	D-amino-acid Oxidase Activity Protein Binding Identical Protein Binding FAD Binding
	Biological Process	Transcription By RNA Polymerase II Regulation Of Gene Expression Histone H4-R3 Methylation Positive Regulation Of Transcription By RNA Polymerase II	Proline Catabolic Process Protein Targeting To Peroxisome D-amino Acid Catabolic Process Cellular Nitrogen Compound Metabolic Process D-serine Catabolic Process Dopamine Biosynthetic Process D-alanine Catabolic Process D-serine Metabolic Process
Pathways		p75NTR negatively regulates cell cycle via SC1	Glyoxylate metabolism and glycine degradation Peroxisomal protein import Peroxisomal protein import
Drugs			3,4-Dihydro-2h-Pyrrolium-5-Carboxylate Imino-Tryptophan Flavin adenine dinucleotide D-Tryptophan Flavin-adenine dinucleotide-N5-isobutyl ketone Benzoic acid Anthranilic acid (2E)-3-(3,4-DIHYDROXYPHENYL)-2-IMINOPROPANOIC ACID
Diseases
GWAS		Acne (severe) ( 24927181) Sleep duration ( 30846698)	Brain morphology (MOSTest) ( 32665545) Mean platelet volume ( 32888494) Nicotine dependence and major depression (severity of comorbidity) ( 30287806)
Interacting Genes		7 interacting genes: CTNNBL1 EIF4E EMX1 MSRB3 NCS1 SERTAD1 SMAD3	5 interacting genes: AOC1 DAOA EP300 PEX5 PRKAB2
Entrez ID		11108	1610
HPRD ID		10425	15917
Ensembl ID		ENSG00000110851	ENSG00000110887
Uniprot IDs		A0A024RBM7 B3KPI0 Q9UKN5	A0A024RBI1 P14920
PDB IDs		2L9Z 3DB5	2DU8 2E48 2E49 2E4A 2E82 2GNZ 3CUK 3G3E 3W4I 3W4J 3W4K 3ZNN 3ZNO 3ZNP 3ZNQ 4QFC 4QFD 5ZJ9 5ZJA 6KBP
Enriched GO Terms of Interacting Partners?
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