ESM1 and VGLL3

Data Source:
BioGRID (two hybrid)

		ESM1	VGLL3
Description		endothelial cell specific molecule 1	vestigial like family member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region	Nucleus
	Molecular Function	Hepatocyte Growth Factor Receptor Binding Integrin Binding Protein Binding Insulin-like Growth Factor Binding
	Biological Process	Angiogenesis Sprouting Angiogenesis Positive Regulation Of Cell Population Proliferation Positive Regulation Of Hepatocyte Growth Factor Receptor Signaling Pathway	Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Cocaine dependence ( 31212010) Familial squamous cell lung carcinoma ( 29924316) Sense of smell ( 26632684)	Adventurousness ( 30643258) Breast cancer ( 29059683) General risk tolerance (MTAG) ( 30643258) HDL cholesterol levels ( 32203549) Menarche (age at onset) ( 27182965 21102462) Metabolite levels ( 23823483) Molybdenum levels ( 26025379) Number of sexual partners ( 30643258) Obesity-related traits ( 23251661) Prostate cancer ( 31562322 26443449) Pubertal anthropometrics ( 23449627) Response to TNF inhibitor in rheumatoid arthritis (change in swollen 28-joint count) ( 30166627) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking status (ever vs never smokers) ( 30643258) Triglyceride levels ( 32203549)
Interacting Genes		15 interacting genes: ADAM12 ANKS1A AQP1 BANP FAM124B FRS3 HDAC7 HOXA1 ITGB2 MEOX2 NRF1 NUFIP2 PRKAB2 VGLL3 YY1	65 interacting genes: CDPF1 CERCAM CNFN CTRC CYSRT1 DTX2 ESM1 FAM168B FRS3 HGS INCA1 KPRP KRTAP1-1 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP13-2 KRTAP15-1 KRTAP19-1 KRTAP19-2 KRTAP19-6 KRTAP19-7 KRTAP3-1 KRTAP3-3 KRTAP4-11 KRTAP4-2 KRTAP5-11 KRTAP5-6 KRTAP6-1 KRTAP6-2 KRTAP9-2 KRTAP9-3 KRTAP9-8 LASP1 LENG8 MDFI MYO15B OXER1 PCSK5 PITX1 PITX2 PLA2G10 POGZ POU2AF1 PRR22 RBPMS RUSC1 SMARCC1 SMOC1 TBX15 TEAD1 TEAD2 TEAD3 TEAD4 TEX37 TRIM42 TSC1 TSPAN4 UFSP1 YPEL3 ZNF34
Entrez ID		11082	389136
HPRD ID		03310	13431
Ensembl ID		ENSG00000164283	ENSG00000206538
Uniprot IDs		Q9NQ30	A8MV65
PDB IDs
Enriched GO Terms of Interacting Partners?
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