TRIM31 and EID3

Data Source:
BioGRID (pull down)

		TRIM31	EID3
Description		tripartite motif containing 31	EP300 interacting inhibitor of differentiation 3
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol	Chromosome, Telomeric Region Nucleus Nucleoplasm Nucleolus Cytoplasm Smc5-Smc6 Complex
	Molecular Function	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding
	Biological Process	Regulation Of Gene Expression Protein Ubiquitination Negative Regulation Of Viral Transcription Innate Immune Response Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Viral Entry Into Host Cell Positive Regulation Of DNA-binding Transcription Factor Activity Interferon-gamma-mediated Signaling Pathway Regulation Of Viral Release From Host Cell	DNA Repair DNA Recombination
Pathways		Interferon gamma signaling	SUMOylation of DNA damage response and repair proteins
Drugs
Diseases
GWAS		Anger ( 24489884) Apolipoprotein A1 levels ( 32203549) Autism spectrum disorder or schizophrenia ( 28540026) Beta-2 microglubulin plasma levels ( 23417110) Blood protein levels ( 28240269) Estimated glomerular filtration rate in diabetes ( 31451708) HDL cholesterol levels ( 32203549) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Isovolumetric relaxation time ( 28394258) Low density lipoprotein cholesterol levels ( 32154731) Mean corpuscular hemoglobin ( 27863252) Neuroticism ( 29255261) Prostate cancer ( 25217961) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Type 1 diabetes and autoimmune thyroid diseases ( 25936594)	Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels) ( 24528284)
Interacting Genes		22 interacting genes: CCT6A EID3 IKBKG MAGEA1 MAGEA2B MKRN3 MNAT1 NLRP3 NSMCE4A TRAF2 TRIM23 TRIM27 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E2 UBE2K UBE2L3 UBE2W USP7 ZSCAN1	4 interacting genes: APPBP2 CREBBP FBXO25 TRIM31
Entrez ID		11074	493861
HPRD ID		10281	17415
Ensembl ID		ENSG00000204616	ENSG00000255150
Uniprot IDs		Q2L6J1 Q9BZY9	A0A140VJI9 Q8N140
PDB IDs		2YSJ 2YSL
Enriched GO Terms of Interacting Partners?
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