MID2 and KRT27

Data Source:
BioGRID (two hybrid)

		MID2	KRT27
Description		midline 2	keratin 27
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Microtubule Extracellular Exosome	Cytosol Intermediate Filament Extracellular Exosome
	Molecular Function	Transcription Coactivator Activity Microtubule Binding Zinc Ion Binding Transferase Activity Enzyme Binding Protein Homodimerization Activity Phosphoprotein Binding	Molecular_function Structural Molecule Activity Protein Binding
	Biological Process	Positive Regulation Of Autophagy Protein Ubiquitination Negative Regulation Of Viral Transcription Protein Localization To Microtubule Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Viral Entry Into Host Cell Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Viral Release From Host Cell	Biological_process Hair Follicle Morphogenesis Keratinization Cornification
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS			Asthma ( 31959851)
Interacting Genes		238 interacting genes: ADAMTSL4 AEN ALDH3B1 ANKS1A AP1M1 AQP1 ARHGEF5 ATRIP AXIN1 BAHD1 BCL6B BLK BLZF1 BRCA1 BRMS1L BYSL C1orf35 CALCOCO2 CARD9 CARHSP1 CBX8 CCDC120 CCDC185 CCDC187 CCDC33 CCDC42 CCHCR1 CDK18 CEP57L1 CFP CHD2 CNNM3 COX5B CPSF4 CRACR2A CREBRF CTSZ DCX DGCR6 DGCR6L DMRT3 DYDC1 EFHC2 EGFL7 EIF1AD ELOA ENKD1 EPN2 ETNK2 FAM107A FAM161A FAM161B FAM214A FAM214B FAM50B FAM90A1 FARS2 FASTKD5 FBF1 FBXL18 FBXW5 FOXD4L3 FRMD6 FSD2 GAS2L2 GAS8 GCC1 GEM GFI1B GMCL1 GOLGA2 GOLGA7 GORASP2 GPANK1 GPKOW GSC2 HAPLN2 HCK HDAC4 HDX HNRNPLL HOXB2 HOXB5 HOXB9 IGBP1 IGFN1 IHO1 IKZF3 IL16 INO80B IQCN ISCU ITGB4 JOSD1 KANK2 KIF1A KIF9 KIFC3 KRT27 KRT31 KRT40 KRT75 KRT76 LAGE3 LENG1 LGALS14 LGALS8 LMNB2 LMNTD2 LMO3 LMO4 LNX1 LONRF1 LRRC45 LZTS1 LZTS2 MAGEA6 MAGOHB MEOX1 MEOX2 METTL17 MFAP1 MID1 MID1IP1 MOS MVP NCOA4 NR1D2 NSMF NXF1 OTUB2 PICK1 PKN1 POLDIP3 PPP1R18 PRDM16 PRPF3 PRPF31 PSMA1 PTCD2 PTPDC1 QARS1 RABGEF1 RANBP3L RCOR3 REL RLN1 RNF6 RORB RPH3AL RPP25L RUNX1T1 RXRB SCNM1 SDCBP SEPTIN1 SHFL SLC25A48 SLC25A6 SNAI1 SNAP47 SPAG5 SPATA24 SPG21 SPRY2 STX11 SYNGAP1 SYT17 TASOR2 TBC1D22B TCAF1 TCEA2 TCEANC TEKT1 THAP7 TMEM14B TOP3B TRIM27 TRIM29 TRIM32 TRIM41 TRIM42 TRIM54 TRIM69 TRPV6 TSGA10 TTC23 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E2 UBE2E3 UBE2K UBE2U UBTD1 UNC45A USP2 USP25 USP54 UTP23 UTP25 WT1-AS ZBTB16 ZBTB24 ZBTB42 ZC2HC1C ZFYVE21 ZGPAT ZIM2 ZNF124 ZNF165 ZNF177 ZNF24 ZNF250 ZNF266 ZNF408 ZNF410 ZNF417 ZNF438 ZNF440 ZNF451 ZNF497 ZNF552 ZNF559-ZNF177 ZNF564 ZNF587 ZNF648 ZNF669 ZNF688 ZNF696 ZNF764 ZNF774 ZNF784 ZNF785 ZNF792 ZRANB1 ZSCAN12	145 interacting genes: AARD ABI2 AMOT ARFIP1 ARHGEF6 ATP6V1D BCAS2 BEX2 BFSP1 BFSP2 C19orf44 C1orf216 C21orf58 CCBE1 CCDC138 CCDC146 CCDC185 CCDC187 CCDC22 CCDC68 CCHCR1 CCNC CEP95 CFAP58 COX5B DPPA3 DTNB DUSP26 EXOC3L1 EXOSC5 FAM107A FAM110A FMNL2 GADD45GIP1 GAS8 GFAP GNG13 GOLGA1 GPS2 GSTK1 HAPLN2 HDAC4 HGS HOOK3 HOXB9 HSPBP1 ICA1L IGF1R INSR INSRR JOSD1 KANK2 KIAA1217 KLHL38 KRT1 KRT2 KRT20 KRT3 KRT4 KRT5 KRT6A KRT6B KRT6C KRT7 KRT71 KRT72 KRT74 KRT75 KRT76 KRT77 KRT78 KRT79 KRT8 KRT81 KRT82 KRT83 KRT85 KRT86 LKAAEAR1 LMNTD2 MATR3 MBD3L2 MID2 MORN4 MOS MTMR9 NDC80 NDUFAF3 NTAQ1 NUP54 NUP58 ODAD3 OIP5 PBX3 PCDHB14 PNN POLL PPP1R18 PRPH PSMC5 RASAL3 RBM41 RCOR3 RNF39 RTP5 RUNX1T1 SCNM1 SDHAF1 SEMA4C SGF29 SLC22A5 SLIRP SMARCC2 SMARCD1 SMARCE1 SNAPIN SSC5D SSX3 SUFU SUOX TBRG4 TEAD4 TEDC2 TEX28 THAP7 TNNT1 TRAF3IP3 TRIML2 TSKS TTC23 TXLNA TXLNB TXN2 USHBP1 USP2 VPS37C WASHC3 XRCC4 ZC3H14 ZFYVE26 ZNF3 ZNF580 ZNF581 ZNF669 ZNF80
Entrez ID		11043	342574
HPRD ID		02191	17244
Ensembl ID		ENSG00000080561	ENSG00000171446
Uniprot IDs		Q6GX22 Q9UJV3	Q7Z3Y8
PDB IDs		2DJA 2DMK
Enriched GO Terms of Interacting Partners?
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