RCC1 and RANBP1

Data Source:
HPRD (in vitro)

		RCC1	RANBP1
Description		regulator of chromosome condensation 1	RAN binding protein 1
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GO Annotations	Cellular Component	Chromatin Condensed Nuclear Chromosome Nucleus Nucleoplasm Cytoplasm Nuclear Membrane Protein-containing Complex	Nucleus Nuclear Envelope Nuclear Pore Cytoplasm Centrosome Cytosol
	Molecular Function	Chromatin Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding Small GTPase Binding Nucleosome Binding Nucleosomal DNA Binding Histone Binding Sulfate Binding Protein Heterodimerization Activity	GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding Cadherin Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Mitotic Spindle Organization Chromosome Segregation Regulation Of Mitotic Nuclear Division Viral Process Ran Protein Signal Transduction Regulation Of Catalytic Activity Spindle Assembly Cell Division Regulation Of Mitotic Spindle Assembly	Signal Transduction Viral Process Positive Regulation Of GTPase Activity Positive Regulation Of Mitotic Centrosome Separation Intracellular Transport
Pathways		Rev-mediated nuclear export of HIV RNA Nuclear import of Rev protein Postmitotic nuclear pore complex (NPC) reformation	Rev-mediated nuclear export of HIV RNA
Drugs			Copper Phenethyl Isothiocyanate
Diseases
GWAS		Night sleep phenotypes ( 27126917) Systolic blood pressure ( 30578418)
Interacting Genes		50 interacting genes: ACTB APLP1 BAG6 CCT7 CDK1 CDK2AP2 CHGB CHKA CSAD CSNK1A1 DDAH2 DYNC1I1 ERCC6 FAF1 FBXO7 FLAD1 GNB2 H2AC18 H2AC20 H2BC21 H3C1 HADHB HMGA1 HOXD8 KMT2B KPNA3 KPNA4 LRIF1 NGFR NTMT1 NUDT21 NUP98 PDHB PKM PTMA RAN RANBP1 RANBP3 RPA1 SDF4 SPRED1 SUMO2 TLE1 TRMT2A TUBB3 UNC119 USP4 WIZ XPO1 ZNF135	7 interacting genes: CD93 KPNB1 MDM2 NUPR1 RAN RANGRF RCC1
Entrez ID		1104	5902
HPRD ID		01559	03110
Ensembl ID		ENSG00000180198	ENSG00000099901
Uniprot IDs		A0A0S2Z3I4 A0A0S2Z404 P18754 Q5T081	A0A140VK94 B3KUP2 B4DE76 D3DX26 F6WQW2 P43487
PDB IDs		1A12 1I2M 5E1B 5E1D 5E1M 5E1O 5E2A 5E2B 5TBK 6DUB	1K5D 1K5G
Enriched GO Terms of Interacting Partners?
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