VAX1 and RPRD1B

Data Source:
BioGRID (two hybrid)

		VAX1	RPRD1B
Description		ventral anterior homeobox 1	regulation of nuclear pre-mRNA domain containing 1B
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleus Nucleoplasm RNA Polymerase II, Holoenzyme
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Intronic Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Chromatin DNA Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Complex Binding Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Neuron Migration Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Neuroblast Proliferation Axon Guidance Central Nervous System Development Brain Development Neuron Differentiation Skeletal Muscle Cell Differentiation Camera-type Eye Development Roof Of Mouth Development	Positive Regulation Of Cell Population Proliferation Regulation Of Cell Cycle Process MRNA 3'-end Processing SnRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Dephosphorylation Of RNA Polymerase II C-terminal Domain
Pathways			RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS		Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Cleft lip with or without cleft palate ( 28054174) Nonsyndromic cleft lip ( 31609978) Nonsyndromic cleft lip with cleft palate ( 28232668) Nonsyndromic cleft lip with or without cleft palate ( 25775280) Orofacial clefts ( 20023658 28054174)
Interacting Genes		14 interacting genes: DVL3 EAF1 ESRRG HECW1 HMBOX1 MLLT3 PICK1 POLR3C PSMB1 RCOR3 RPRD1B SDCBP2 SPANXN2 USP20	19 interacting genes: BIN3 CDCA8 DDIT4L HMG20A HOXC4 NUTF2 PFDN6 PIP4K2B PSMB1 RASSF3 RPRD1A SPG21 STEEP1 TERF2 TNPO2 TUBGCP4 UBE2I VAX1 VPS37C
Entrez ID		11023	58490
HPRD ID		16052	08513
Ensembl ID		ENSG00000148704	ENSG00000101413
Uniprot IDs		Q5SQQ9	Q9NQG5
PDB IDs			4FLA 4FU3 4HFG 4NAD 4Q94 4Q96
Enriched GO Terms of Interacting Partners?
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