CKAP4 and PLXNC1

Data Source:
BioGRID (affinity chromatography technology)

		CKAP4	PLXNC1
Description		cytoskeleton associated protein 4	plexin C1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Lipid Droplet Cytosol Cytoskeleton Plasma Membrane Membrane Integral Component Of Membrane Nuclear Speck Azurophil Granule Membrane Specific Granule Membrane Cytoplasmic Ribonucleoprotein Granule Lamellar Body Perinuclear Region Of Cytoplasm Extracellular Exosome	Semaphorin Receptor Complex Plasma Membrane Integral Component Of Plasma Membrane Membrane
	Molecular Function	RNA Binding	Signaling Receptor Binding Protein Binding Semaphorin Receptor Activity
	Biological Process	Neutrophil Degranulation Post-translational Protein Modification Cellular Protein Metabolic Process	Cell Adhesion Negative Regulation Of Cell Adhesion Regulation Of Cell Shape Regulation Of Cell Migration Regulation Of GTPase Activity Positive Regulation Of Axonogenesis Semaphorin-plexin Signaling Pathway Involved In Axon Guidance
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Surfactant metabolism Neutrophil degranulation Post-translational protein phosphorylation	Other semaphorin interactions
Drugs
Diseases
GWAS		Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Metabolite levels ( 23823483) Refractive error ( 32231278)	Alopecia areata ( 25608926) Asthma ( 31959851 32296059) Blood protein levels ( 30072576 29875488 28240269) Diastolic blood pressure ( 30578418) Major depressive disorder ( 29317602) Multiple sclerosis ( 31604244) Pulse pressure ( 30578418) Remission after SSRI treatment in MDD or neuroticism ( 29559929) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309) Response to ranibizumab in age-related macular degeneration (exudative) ( 30054556)
Interacting Genes		13 interacting genes: ASCC2 ATF4 DKK1 HAMP LINC01554 MLH1 MVP NDUFB7 NKX3-1 PLAT THOC7 TSNAX WASHC3	1 interacting genes: SEMA7A
Entrez ID		10970	10154
HPRD ID		16717	05036
Ensembl ID		ENSG00000136026	ENSG00000136040
Uniprot IDs		A0A024RBH2 Q07065	O60486
PDB IDs			3KUZ 3NVN 3NVQ 6VXK
Enriched GO Terms of Interacting Partners?
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