RAB40B and ANKRD27

Data Source:
BioGRID (two hybrid)

		RAB40B	ANKRD27
Description		RAB40B, member RAS oncogene family	ankyrin repeat domain 27
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Endosome Plasma Membrane Synaptic Vesicle Perinuclear Region Of Cytoplasm	Lysosome Early Endosome Late Endosome Cytosol Plasma Membrane Membrane Transport Vesicle Cytoplasmic Vesicle Membrane Melanosome Neuron Projection Tubular Endosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding	SNARE Binding Guanyl-nucleotide Exchange Factor Activity GTPase Activator Activity Protein Binding Small GTPase Binding
	Biological Process	Protein Ubiquitination Intracellular Signal Transduction Protein Localization To Plasma Membrane Toxin Transport	Positive Regulation Of Neuron Projection Development Protein Transport Negative Regulation Of SNARE Complex Assembly Endosome To Melanosome Transport Positive Regulation Of GTPase Activity Early Endosome To Late Endosome Transport Neuron Projection Morphogenesis Positive Regulation Of Dendrite Morphogenesis Retrograde Transport, Endosome To Plasma Membrane
Pathways		RAB geranylgeranylation	RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Colorectal cancer or advanced adenoma ( 30510241)	Blood protein levels ( 30072576) Eosinophilic esophagitis ( 25407941) Gut microbiota relative abundance (Bacteroides) ( 33208821) Major depressive disorder ( 23377640) Red cell distribution width ( 27863252 28957414) Systemic lupus erythematosus ( 33536424)
Interacting Genes		6 interacting genes: ANKRD27 APP EFEMP2 FHIT FHL3 WFDC1	5 interacting genes: RAB40A RAB40B RAB40C SMAD1 VAMP7
Entrez ID		10966	84079
HPRD ID		11472	10650
Ensembl ID		ENSG00000141542	ENSG00000105186
Uniprot IDs		Q12829	Q96NW4
PDB IDs			4B93 4CYM 4CZ2 6TL0
Enriched GO Terms of Interacting Partners?
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