SRSF8 and TRA2B

Data Source:
BioGRID (two hybrid)

		SRSF8	TRA2B
Description		serine and arginine rich splicing factor 8	transformer 2 beta homolog
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Nuclear Speck	Nucleus Nuclear Inner Membrane Nucleoplasm Spliceosomal Complex Protein-containing Complex Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Binding Protein Binding	RNA Binding MRNA Binding Protein Binding Protein Domain Specific Binding Pre-mRNA Binding Identical Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome	Response To Reactive Oxygen Species RNA Splicing, Via Transesterification Reactions Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Cerebral Cortex Regionalization Regulation Of RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome Cellular Response To Glucose Stimulus Embryonic Brain Development
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Height ( 31562340) Menarche (age at onset) ( 27182965 21102462 25231870) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		8 interacting genes: APP CLK3 KRTAP12-2 SREK1 SRPK1 SRPK2 SRSF3 TRA2B	110 interacting genes: CDK6 CLK1 CLK3 EPM2AIP1 HINFP HIPK3 HNRNPA1 IVNS1ABP LUM MAGOHB MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I MYPOP NGFR NXF1 PCDHB14 RBMX RBMXL2 RBMY1A1 RBMY1F RBMY1J RNPS1 SREK1 SRPK1 SRPK2 SRSF1 SRSF10 SRSF2 SRSF3 SRSF4 SRSF6 SRSF8 SRSF9 TNPO3 U2AF1 U2AF1L5 YTHDC1 YWHAG YWHAZ ZRANB2
Entrez ID		10929	6434
HPRD ID		04466	04097
Ensembl ID		ENSG00000263465	ENSG00000136527
Uniprot IDs		A0A024R3A8 Q9BRL6	P62995
PDB IDs		2DNM	2CQC 2KXN 2RRA 2RRB
Enriched GO Terms of Interacting Partners?
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