SUGT1 and S100A6

Data Source:
HPRD (in vitro, in vivo)

		SUGT1	S100A6
Description		SGT1 homolog, MIS12 kinetochore complex assembly cochaperone	S100 calcium binding protein A6
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GO Annotations	Cellular Component	Ubiquitin Ligase Complex Kinetochore Nucleus Cytosol Protein-containing Complex	Ruffle Extracellular Region Nucleus Nuclear Envelope Cytoplasm Cytosol Plasma Membrane Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Perinuclear Region Of Cytoplasm Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Protein Binding	Calcium Ion Binding Protein Binding Tropomyosin Binding Zinc Ion Binding Ion Transmembrane Transporter Activity Protein Homodimerization Activity S100 Protein Binding Calcium-dependent Protein Binding
	Biological Process	Mitotic Cell Cycle Regulation Of Protein Stability Positive Regulation By Host Of Symbiont Catalytic Activity Protein Stabilization	Signal Transduction Axonogenesis Ion Transmembrane Transport Positive Regulation Of Fibroblast Proliferation
Pathways		The NLRP3 inflammasome Purinergic signaling in leishmaniasis infection
Drugs			Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS			HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
Interacting Genes		17 interacting genes: BUB3 CSNK2A1 DSN1 HSP90AA1 HSPA4 MIS12 NR4A1 NSL1 PAXIP1 PHLPP1 PLK1 PMF1 PTGER4 S100A6 S100B S100P SKP1	17 interacting genes: ANXA11 ANXA2 CACYBP CEP20 CEP43 FAM25A FAM25C FAM25G FKBP4 GAPDH MDM2 OFD1 PEX5 PPID S100B SUGT1 TP53
Entrez ID		10910	6277
HPRD ID		09160	00237
Ensembl ID		ENSG00000165416	ENSG00000197956
Uniprot IDs		A8K7W3 B4DYC6 Q9Y2Z0	P06703
PDB IDs		1RL1	1K8U 1K96 1K9K 1K9P 2M1K 4YBH
Enriched GO Terms of Interacting Partners?
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