CERS1 and BDKRB1

Data Source:
BioGRID (two hybrid)

		CERS1	BDKRB1
Description		ceramide synthase 1	bradykinin receptor B1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Neuron Projection
	Molecular Function	N-acyltransferase Activity Sphingosine N-acyltransferase Activity	G Protein-coupled Receptor Activity Bradykinin Receptor Activity Protein Binding Peptide Binding
	Biological Process	Sphingolipid Biosynthetic Process Cellular Response To Drug Cellular Response To Mycotoxin Ceramide Biosynthetic Process Negative Regulation Of Telomerase Activity Cellular Response To UV-A Cellular Response To Dithiothreitol	Negative Regulation Of Protein Phosphorylation Positive Regulation Of Leukocyte Migration Inflammatory Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Response To Mechanical Stimulus Cell Migration Sensory Perception Of Pain Negative Regulation Of Cell Growth Response To Lipopolysaccharide Negative Regulation Of Blood Pressure Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Pathways		Sphingolipid de novo biosynthesis	Peptide ligand-binding receptors G alpha (q) signalling events G alpha (i) signalling events
Drugs			Ramipril Captopril Zinc Enalaprilat Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS			Metabolite levels ( 23823483)
Interacting Genes		5 interacting genes: BDKRB1 DRD2 HTR4 LTB4R2 MAPK6	32 interacting genes: C1orf43 CERS1 DNAJB1 GABBR1 GNAQ GRIN1 HHATL HILPDA HTT INSIG1 LAPTM4B LRRC4C MBOAT7 MDC1 NAGPA NAP1L4 NDFIP1 NF2 OAZ2 RAE1 RETREG1 RTN4 SLC25A28 SLC39A14 SLC44A2 SLC6A8 TMEM42 TMX2 TRAM1L1 TRAT1 UQCRC1 ZNF22
Entrez ID		10715	623
HPRD ID		12114	02639
Ensembl ID		ENSG00000223802	ENSG00000100739
Uniprot IDs		B4DE47 P27544 Q5XG75	P46663
PDB IDs
Enriched GO Terms of Interacting Partners?
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