IVNS1ABP and PFN2

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		IVNS1ABP	PFN2
Description		influenza virus NS1A binding protein	profilin 2
Image
GO Annotations	Cellular Component	Nucleoplasm Transcription Regulator Complex Spliceosomal Complex Cytosol Cytoskeleton	Cytoplasm Cytoskeleton Extracellular Exosome
	Molecular Function	Protein Binding	Actin Binding Actin Monomer Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding ATPase Activity
	Biological Process	Transcription By RNA Polymerase III RNA Splicing Response To Virus Viral Process Negative Regulation Of Protein Ubiquitination Negative Regulation Of Intrinsic Apoptotic Signaling Pathway	Negative Regulation Of Epithelial Cell Migration Actin Cytoskeleton Organization Regulation Of Actin Filament Polymerization Negative Regulation Of Actin Filament Polymerization Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Actin Filament Bundle Assembly Positive Regulation Of ATPase Activity Positive Regulation Of Peptidyl-serine Phosphorylation Protein Stabilization Positive Regulation Of Stress Fiber Assembly Negative Regulation Of Ruffle Assembly
Pathways			Signaling by ROBO receptors RHO GTPases Activate Formins RHO GTPases Activate Formins
Drugs			Triglyme Pentaglyme
Diseases
GWAS		Lead levels ( 26025379)	Fish- and plant-related diet ( 32066663)
Interacting Genes		11 interacting genes: AHR CHD3 ENO1 KLHL20 PFN2 POLR1H RPL6 SYNCRIP TRA2B TRIM14 VIM	34 interacting genes: ACTB ACTG1 ANTKMT BIRC2 CCDC113 DDX11 DLST DNM1 EEF1A1 ERCC6 EVL FHOD1 FLT3LG FMNL1 GOLGB1 HTT IK IVNS1ABP MSANTD3 MYPOP NDUFB8 PLAUR PTPRS RAP1GAP RNF146 ROCK1 RPS10 SEPTIN5 SGTA SNTA1 SYN1 TERF1 VASP WDR33
Entrez ID		10625	5217
HPRD ID		10004	01451
Ensembl ID		ENSG00000116679	ENSG00000070087
Uniprot IDs		Q9Y6Y0	P35080
PDB IDs		5YY8 6N34 6N3H	1D1J
Enriched GO Terms of Interacting Partners?
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