STAMBP and CHMP5

Data Source:
BioGRID (two hybrid)

		STAMBP	CHMP5
Description		STAM binding protein	charged multivesicular body protein 5
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Endosome Early Endosome Cytosol Plasma Membrane Membrane Cleavage Furrow Extracellular Exosome	Nucleus Multivesicular Body Cytosol Endosome Membrane Extracellular Exosome
	Molecular Function	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Metallopeptidase Activity Protein Domain Specific Binding Metal Ion Binding Lys63-specific Deubiquitinase Activity Isopeptidase Activity	Protein Binding Cadherin Binding
	Biological Process	Mitotic Cytokinesis Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Cell Population Proliferation Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Protein Deubiquitination Protein Phosphopantetheinylation Negative Regulation Of Ras Protein Signal Transduction Protein K63-linked Deubiquitination	Regulation Of Receptor Recycling Vesicle Budding From Membrane Nucleus Organization Lysosome Organization Mitotic Metaphase Plate Congression Endosome To Lysosome Transport Regulation Of Centrosome Duplication Protein Transport Endosomal Transport Viral Life Cycle Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Midbody Abscission Cellular Response To Lipopolysaccharide Cellular Response To Muramyl Dipeptide Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly ESCRT III Complex Disassembly
Pathways		Metalloprotease DUBs	Budding and maturation of HIV virion Endosomal Sorting Complex Required For Transport (ESCRT)
Drugs
Diseases
GWAS		Anti-saccade response ( 29064472) Blood metabolite levels ( 26401656) Serum metabolite levels ( 23093944)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Erectile dysfunction and prostate cancer treatment ( 20932654)
Interacting Genes		45 interacting genes: ALAS1 AMN APOBEC3A BMPR1B CASR CHMP1A CHMP1B CHMP2A CHMP3 CHMP4A CHMP4B CHMP4C CHMP5 CLTC CTNNBL1 CYP2C9 EPS15 GRAP2 GRB2 IL1RL2 ITGA5 MAP2K5 MAP3K2 NLRP3 NLRP7 NTPCR PJA1 RECQL5 RNF11 SMAD2 SMAD6 SMAD7 SNCA SPG7 STAM STAM2 TNFRSF1A TP53 TRAF6 TRIP13 UACA UBC UBE2S USP21 USP28	16 interacting genes: APPBP2 CHMP1B CHMP4A CHMP4B GTF3A MITD1 NOD2 PDCD10 RPL38 SMARCA4 STAMBP URGCP VPS4B VTA1 ZNF142 ZNF91
Entrez ID		10617	51510
HPRD ID		05877	15408
Ensembl ID		ENSG00000124356	ENSG00000086065
Uniprot IDs		A0A140VK54 O95630	Q9NZZ3
PDB IDs		2XZE 3RZU 3RZV 5IXF	2LXM 3ULY 3UM0 3UM1 3UM2 4TXR
Enriched GO Terms of Interacting Partners?
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