CENPB and CENPW

Data Source:
BioGRID (fluorescent resonance energy transfer)

		CENPB	CENPW
Description		centromere protein B	centromere protein W
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Condensed Chromosome, Centromeric Region Nucleus Nucleoplasm Chromosome Pericentric Heterochromatin Nuclear Body	Chromosome, Centromeric Region Kinetochore Condensed Chromosome Kinetochore Nucleoplasm Nucleolus Nuclear Matrix
	Molecular Function	DNA Binding Chromatin Binding Satellite DNA Binding Centromeric DNA Binding Sequence-specific DNA Binding	DNA Binding Protein Binding Protein Heterodimerization Activity
	Biological Process		Mitotic Cell Cycle Chromosome Segregation CENP-A Containing Nucleosome Assembly Chromosome Organization Cell Division Kinetochore Assembly
Pathways			Deposition of new CENPA-containing nucleosomes at the centromere
Drugs
Diseases
GWAS			Birth weight ( 31043758) Bone mineral density (paediatric, skull) ( 24945404) Bone mineral density (paediatric, total body less head) ( 24945404) Bone mineral density (paediatric, upper limb) ( 24945404) Brain morphology (MOSTest) ( 32665545) C-reactive protein levels ( 30388399) Coronary artery disease ( 29212778) Cortical surface area (global PC1) ( 32198502) Cortical surface area (visual PC2) ( 32198502) Diastolic blood pressure ( 27841878) Feeling nervous ( 29500382) Food addiction ( 27106561) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Height ( 28552196) Hip circumference adjusted for BMI ( 25673412) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Intracranial volume ( 22504418) Intraocular pressure ( 29617998) Liver transplant-free survival in primary sclerosing cholangitis (time to event) ( 28779025) Lung function (FVC) ( 30061609) Male-pattern baldness ( 29146897 27182965 28196072) Menarche (age at onset) ( 27182965 25231870) Monobrow ( 27182965) Neurociticism ( 29500382) Neuroticism ( 29255261) Occipital lobe volume ( 31396565) Optic disc size ( 31809533) Pulse pressure ( 27841878) QT interval ( 29213071) Subcortical brain region volumes ( 25607358) Subcortical volume (MOSTest) ( 32665545) Systolic blood pressure ( 27841878) Type 1 diabetes ( 30659077 30572963) Type 2 diabetes ( 30297969 32499647 28869590)
Interacting Genes		20 interacting genes: ADRB2 ANXA7 APP CDKN1A CENPW CSNK2B FBXO25 GADD45A GFI1B GSK3B HAND2 NR3C1 PARP1 PARP2 PIN1 RPS6KA6 SH2D3A SMN1 TAC1 TK1	6 interacting genes: BTRC CENPB CENPT CUL1 H3C1 NPM1
Entrez ID		1059	387103
HPRD ID		00314	16660
Ensembl ID		ENSG00000125817	ENSG00000203760
Uniprot IDs		P07199	A0A0A0MRK5 Q5EE01
PDB IDs		1BW6 1HLV 1UFI 6KDR
Enriched GO Terms of Interacting Partners?
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